The most promising devices of those for radionuclide diagnosis that can be used for control of nuclides incorporated in the human body during a radiation incident are hybrid scanners. The authors made the calibration of devices of this type to register a mixture of 137Cs and 134Cs. The minimum detected activity was 40 nCi. A methodological error of measurements was +/- 3%. A mathematical criterion for optimization of the geometry of measurements was drawn for devices, including the methodological and statistical components of a total error. This criterion was used for finding optimum sizes of a slot collimator of the device.
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