Gas have long been used in radiological examinations, in particular for the diagnostic evaluation of gastrointestinal diseases. However, not until the introduction of digital subtraction angiography was carbon dioxide also used with success for angiography of arteries. In order to advice exact and reproducible dosage of the gas with freely selectable injection parameters, a carbon dioxide gas metering device was developed. The principle of gas metering is based on the measurement of the pressure gradient of the gas across a defined pneumatic resistance. The gas metering devices was tested in 15 animal experiments to produce survey and selective angiograms.
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