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Usefulness of multimodal MR imaging in the differential diagnosis of HaNDL and acute ischemic stroke. | LitMetric

AI Article Synopsis

  • HaNDL is a rare syndrome that can cause temporary headaches and neurological deficits that may look like a stroke.
  • Neuroimaging helped correctly identify a HaNDL patient, preventing unnecessary treatment with thrombolytic drugs, which are ineffective for this condition.
  • The case underscores the importance of advanced imaging techniques in diagnosing HaNDL early and highlights findings of cerebral hypoperfusion associated with the syndrome.

Article Abstract

Background: Syndrome of transient Headache and Neurological Deficits with cerebrospinal fluid Lymphocytosis (HaNDL) is a rare disease which can present with focal neurological deficits and mimic stroke. A neurologist-on-duty faced with a HaNDL patient in the first hours might erroneously decide to use thrombolytic drugs, a non-innocuous treatment which has no therapeutic effect on this syndrome.

Case Presentation: We present a case where neuroimaging, together with the clinical picture, led to a presumed diagnosis of HaNDL avoiding intravenous thrombolysis.

Conclusions: This report shows the usefulness of multimodal MR imaging in achieving early diagnosis during an acute neurological attack of HaNDL. Our experience, along with that of others, demonstrates that neuroimaging tests reveal the presence of cerebral hypoperfusion in HaNDL syndrome.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017035PMC
http://dx.doi.org/10.1186/1471-2377-10-120DOI Listing

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