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The Challenges of Forensic Medicine in Victim Identification in the Wake of the October 7th (2023) Mass Casualty Event.

Isr Med Assoc J

November 2024

Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel, Reichman University, Herzliya, Israel.

Background: The massive terrorist attack on a mixed population of civilians, soldiers, and foreigners on October 7, 2023, resulted in 1200 casualties and led to many major personal identification issues. At the Israel National Center for Forensic Medicine (INCFM), addressing the mass casualty incidents required precision that included technical, ethical, and humanitarian dimensions. Many obstacles arose that were attributable to the vast number and diversity of victims and the heavy workload in the setting of a small forensic team.

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Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) from 2011 to 2024: A comprehensive bibliometric review.

Autoimmun Rev

December 2024

Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Ramat Gan, Israel; Reichmann University, Herzliya, Israel.

Introduction: Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) encompasses a spectrum of autoimmune and inflammatory conditions triggered by various adjuvants, leading to significant health challenges. This study aims to understand the research landscape and future directions of ASIA through a comprehensive bibliometric analysis.

Methods: Relevant original articles were retrieved from the Scopus database, focusing on publications from 2011 to July 2024.

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The expression "Autoimmune/inflammatory syndrome induced by adjuvants (ASIA)" was coined by Shoenfeld and colleagues in 2011. It defines a group of immune-mediated disorders that arise in people, with a genetic predisposition, following exposure to adjuvant agents. This syndrome has been reported after contact with silicone implants, medications, infections, metals, vaccines, and other substances.

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Introduction And Importance: The Autoimmune/inflammatory Syndrome Induced by Adjuvants (ASIA) is a recently recognized entity characterized by a constellation of nonspecific symptoms that develop after exposure to adjuvants. Adjuvants can include vaccines, silicone, and other foreign substances. Here, we present the case of a 31-year-old woman who developed ASIA syndrome following breast implants and booster vaccinations, emphasizing the diagnostic challenges and treatment considerations.

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Article Synopsis
  • Chronic Fatigue Syndrome (CFS), Fibromyalgia (FM), and related conditions, including Long-COVID and others, share symptoms like fatigue, pain, and cognitive issues, often influenced by autonomic dysfunction and immune responses.
  • The study reviews literature from January 1990 to January 2024, analyzing 172 articles focused on hearing issues, such as tinnitus and vertigo, associated with these conditions.
  • Symptoms related to hearing disturbances are highly variable, with cochlear problems being the most common, while mechanisms like autoimmune reactions and virus effects on the nervous system are proposed as potential causes.
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