The aim of this study was to analyze in vitro the debriding ability of an Er:YAG laser system (2,940 nm) equipped with a newly designed radial and stripped tip of 400 µm diameter by scanning electron microscopy (SEM). A total of 80 single-rooted extracted human teeth were endodontically prepared with rotary instrumentation and standardized chemical irrigation using 5.25% sodium hypochlorite. At the end of mechanical instrumentation, four different final protocols were used. Group 1 was irrigated for 2 min with saline water as a control group. Groups 2, 3 and 4 were irradiated with an Er:YAG laser at 25 mJ and 15 Hz with a pulse duration of 50 μs and laser spray off using the tip in the coronal opening of the wet root canal. Different solutions and irradiation times were used: group 2 20 s, laser irradiation in sterile distilled water, wet canal; group 3 20 s, laser irradiation in 17% EDTA, wet canal; and group 4 40 s, laser irradiation in 17% EDTA, wet canal. Debridement of and smear layer removal from the apical third of root canals were evaluated by SEM. The study showed that standardized instrumentation, followed by a final Er:YAG laser irradiation in wet canals with EDTA irrigation resulted in more cleaning of the root canal walls and a higher quantity of open tubules in comparison with the traditional irrigation method.
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http://dx.doi.org/10.1007/s10103-010-0858-x | DOI Listing |
Lasers Med Sci
January 2025
Hospital for Skin Diseases, Shandong First Medical University, Jinan, China.
To investigate the efficacy and safety of picosecond (PS) and nanosecond (NS) 1064-nm neodymium-doped yttrium aluminum garnet (Nd: YAG) laser in treating Café-au-lait macules (CALMs). We retrospectively analyzed the medical records of patients with CALMs, who were treated with PS or NS 1064-nm lasers from January 2020 to January 2022. The efficacy was determined based on the before and after pictures by two independent investigators.
View Article and Find Full Text PDFLasers Med Sci
January 2025
Cornell University, Ithaca, USA.
Purpose: Photobiomodulation (PBM) is a non-invasive therapeutic procedure that consists of irradiating a local area of the skin with red and near-infrared lasers or light emitting diodes (LEDs). Local PBM has been studied as a method to improve exercise performance and recovery. This review aims to evaluate the efficacy of whole-body PBM for exercise performance and recovery, comparing its findings to the established effects of localized PBM.
View Article and Find Full Text PDFAnal Chem
January 2025
Guangdong Key Laboratory of Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, P. R. China.
Understanding the molecular energy metabolism of single cells in the nucleolus stress response induced by mild-photothermal therapy (mPTT) is of great importance for investigating the photothermal lethal mechanism. Herein, we successfully fabricated a "turn-on"-type fluorescent nanoprobe based on the fluorescently labeled aptamers (FAM-ATP-apt and Cy3-GTP-apt) and TiCT MXene. When the adapters on the nanoprobes bonded to intracellular ATP and GTP, the fluorescence of the nanoprobes was restored.
View Article and Find Full Text PDFJ Mater Chem B
January 2025
National Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu, 610065, P. R. China.
Wound healing is a complex and dynamic biological process that requires meticulous management to ensure optimal outcomes. Traditional wound dressings, such as gauze and bandages, although commonly used, often fall short in their frequent need for replacement, lack of real-time monitoring and absence of anti-inflammatory and antibacterial properties, which can lead to increased risk of infection and delayed healing. Here, we address these limitations by introducing an innovative hydrogel dressing, named PHDNN6, to combine wireless Bluetooth temperature monitoring and light-triggered nitric oxide (NO) release to enhance wound healing and management.
View Article and Find Full Text PDFJ Nanobiotechnology
January 2025
School of Medical Imaging, Xuzhou Medical University, Xuzhou, 221004, China.
With the progress of atherosclerosis (AS), the arterial lumen stenosis and compact plaque structure, the thickening intima and the narrow gaps between endothelial cells significantly limit the penetration efficiency of nanoprobe to plaque, weakening the imaging sensitivity and therapy efficiency. Thus, in this study, a HO-NIR dual-mode nanomotor, Gd-doped mesoporous carbon nanoparticles/Pt with rapamycin (RAPA) loading and AntiCD36 modification (Gd-MCNs/Pt-RAPA-AC) was constructed. The asymmetric deposition of Pt on Gd-MCNs catalyzed HO at the inflammatory site to produce O, which could promote the self-motion of the nanomotor and ease inflammation microenvironment of AS plaque.
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