Aqueous and methanol extracts of dry sage, rosemary, basil, parsley, chili, garlic and onion were analyzed to investigate their anti-oxidant and anti-glycant activities and in vitro inhibitory potential against enzymes involved in glycemic regulation. The aqueous extracts of rosemary and sage were the richest in phenolic compounds and showed the highest ability in binding iron and inhibiting DPPH, superoxide radicals and advanced glycation end-product production, lipid peroxidation, and the activity of α-glucosidase and α-amylase. On the other hand, the methanol extracts of both these Labiatae were less efficient than those of garlic, onion, parsley and chili in scavenging hydroxyl radicals. As far as protein glycation is concerned, methanol extracts were more effective in inhibiting the production of Amadori compounds and the aqueous ones in preventing advanced glycation end-product formation. Therefore these spices may be preventive not only against cardiovascular diseases but also type 2 diabetes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/09637486.2010.529068 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Broccoli () leaves exhibit significant antidiabetic potential in alloxan-induced diabetic rats: the putative role of ABC vacuolar transporter for accumulation of Quercetin and Kaempferol.
Front Pharmacol
December 2024
Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan.
Background: The global prevalence of diabetes among adults over 18 years of age is expected to increase from 10.5% to 12.2% (between 2021 and 2045).
View Article and Find Full Text PDFWound healing activity of green synthesized copper nanoparticles through cell proliferation-migration, antimicrobial effects, and nitric oxide triggering.
Arch Razi Inst
June 2024
Faculty of Pharmacy, Eastern Mediterranean University, Famagusta, Mersin 10, Turkey.
The present experimental study aimed to assess the wound healing and anti-inflammatory effects of green synthesized copper nanoparticles (CuNPs) by the methanol extract of (Boiss), as a plant with various pharmacological effects, such as anti-inflammatory and antimicrobial effects, in traditional and modern medicine. The precipitation approach was used for the green synthesis of CuNPs by mixing the methanol and copper sulfate solution. Cell viability and fibroblast proliferation assay were performed by MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide) assay.
View Article and Find Full Text PDFAntinociceptive and anti-inflammatory activities of the methanol extract of Korovin in a rat model.
Arch Razi Inst
June 2024
Department of Pharmacy Practice, Faculty of Pharmacy, University of Sindh, Jamshoro, Pakistan.
Today, the current chemical agents used for the management of pain cause numerous complications. They are associated with the occurrence of disorders in the digestive system, damage to the kidney, or addiction, which has prompted individuals to seek novel drugs that, apart from removing the side effects, are cost-effective and available. The present survey aimed to assess the antinociceptive and anti-inflammatory activity of Korovin methanolic extract (FEME) in male Swiss mice.
View Article and Find Full Text PDFEvaluation of PFAS extraction and analysis methods for biosolids.
Talanta
December 2024
Interdisciplinary Ecological Sciences & Engineering, Purdue University, West Lafayette, IN, 47907, USA; Department of Environmental & Ecological Engineering, Purdue University, West Lafayette, IN, 47907, USA; Department of Agronomy, Purdue University, West Lafayette, IN, 47907, USA. Electronic address:
Per- and polyfluoroalkyl substances (PFAS) in the environment is a growing concern leading to a focus on PFAS occurrence in biosolids, a byproduct of wastewater treatment processes, often applied to improve soil health. This led to the need for analytical method development for assessing PFAS in biosolids. This study compares three methods for PFAS quantitation, evaluating solvent extraction, clean-up techniques, and final injection solvents.
View Article and Find Full Text PDFApproaches for the Inactivation of .
Appl Biosaf
December 2024
Department of Microbiology and Immunology; University of Louisville School of Medicine, Louisville, Kentucky, USA.
Introduction: is the gram-negative, facultative intracellular bacterium that causes the disease known as plague. Due to the risk for aerosol transmission, a low infectious dose, and the acute and lethal nature of pneumonic plague, research activities with require Biosafety Level 3 (BSL-3) facilities to provide the appropriate safeguards to minimize accidental exposures and environmental release. However, many experimental assays cannot be performed in BSL-3 due to equipment availability, and thus require removal of samples from the BSL-3 laboratory to be completed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!