Background: Task-oriented therapies such as treadmill exercise can improve gait velocity after stroke, but slow velocities and abnormal gait patterns often persist, suggesting a need for additional strategies to improve walking.
Objectives: To determine the effects of a 6-week visually guided, impedance controlled, ankle robotics intervention on paretic ankle motor control and gait function in chronic stroke.
Methods: This was a single-arm pilot study with a convenience sample of 8 stroke survivors with chronic hemiparetic gait, trained and tested in a laboratory. Subjects trained in dorsiflexion-plantarflexion by playing video games with the robot during three 1-hour training sessions weekly, totaling 560 repetitions per session. Assessments included paretic ankle ranges of motion, strength, motor control, and overground gait function.
Results: Improved paretic ankle motor control was seen as increased target success, along with faster and smoother movements. Walking velocity also increased significantly, whereas durations of paretic single support increased and double support decreased.
Conclusions: Robotic feedback training improved paretic ankle motor control with improvements in floor walking. Increased walking speeds were comparable with reports from other task-oriented, locomotor training approaches used in stroke, suggesting that a focus on ankle motor control may provide a valuable adjunct to locomotor therapies.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565577 | PMC |
http://dx.doi.org/10.1177/1545968310388291 | DOI Listing |
Bioact Mater
May 2025
Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), Calle Sor Juana Inés de la Cruz 3, 28049, Madrid, Spain.
Millions of patients and their caretakers live and deal with the devastating consequences of spinal cord injury (SCI) worldwide. Despite outstanding advances in the field to both understand and tackle these pathologies, a cure for SCI patients, with their peculiar characteristics, is still a mirage. One of the most promising therapeutic strategies to date for these patients involves the use of epidural electrical stimulation.
View Article and Find Full Text PDFiScience
January 2025
Key Laboratory of Brain Functional Genomics (Ministry of Education), East China Normal University, Shanghai 200062, China.
Learned action sequences are suggested to be organized hierarchically, but how the various hierarchical levels are processed by different cortical regions remains largely unknown. By training monkeys to perform heterogeneous saccade sequences, we investigated the role of the dorsolateral prefrontal cortex (DLPFC) and the lateral intraparietal cortex (LIP) in sequence planning and execution. The electrophysiological recording revealed that sequence-level initiation information was mostly signaled by DLPFC neurons, whereas subsequence-level transition was largely encoded by LIP neurons.
View Article and Find Full Text PDFActa Naturae
January 2024
Research Center of neurology, Ministry of Science and Higher Education of the Russian Federation, Moscow, 125367 Russian Federation.
Amyotrophic lateral sclerosis (ALS) is a severe disease of the central nervous system (CNS) characterized by motor neuron damage leading to death from respiratory failure. The neurodegenerative process in ALS is characterized by an accumulation of aberrant proteins (TDP-43, SOD1, etc.) in CNS cells.
View Article and Find Full Text PDFProc Biol Sci
January 2025
Animal Physiology Unit, Institute of Neurobiology, University of Tübingen, Auf der Morgenstelle 28, Tübingen 72076, Germany.
Like humans and many other animal species, birds exhibit left-right asymmetries in certain behaviours due to differences in hemispheric brain functions. While the lateralization of sensory and motor functions is well established in birds, the potential lateralization of high-level executive control functions, such as volitional attention, remains unknown. Here, we demonstrate that carrion crows exhibit more pronounced volitional (endogenous) attention for stimuli monocularly viewed with the left eye and thus in the left visual hemifield.
View Article and Find Full Text PDFJ Neuropsychol
January 2025
Department of Health, Medical and Neuropsychology, Leiden University, Leiden, The Netherlands.
Up to 45% of patients with Parkinson's disease (PD) experience impulse control disorders (ICDs), characterized by a loss of voluntary control over impulses, drives or temptations. This study aimed to investigate whether previously identified genetic and psychiatric risk factors interact towards the development of ICDs in PD. A total of 278 de novo PD patients (ICD-free at enrollment) were selected from the Parkinson's Progression Markers Initiative database.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!