Background: The most common cause of hypopituitarism is pituitary adenoma. However, in the case of suprasellar masses different etiologies are possible. We report an unusual case of primary suprasellar lymphoma presented with hypopituitarism.
Case Presentation: A 26 year old woman presented with amenorrhea, galactorrhea and neurological disorders. Also, the laboratory work-up revealed partial hypopituitarism. The magnetic resonance imaging of the head showed a suprasellar mass. A presumptive diagnosis of granulomatous processes was made and the patient was given steroid therapy. Repeated brain MRI detected new lesions in the brain with regression of the suprasellar mass. Stereotactic biopsy of the paraventricular lesion revealed the diagnosis of B-cell lymphoma.
Conclusion: This case presentation reports a rare cause of hypopituitarism. Primary suprasellar lymphoma is extremely rare and represented a real diagnostic challenge. Besides, suprasellar masses are varied in aetiology and can present diagnostic problems for a radiologist. Also, because of the increased incidence of PCNSL, lymphoma must be kept in mind in the differential diagnosis of lesions in the suprasellar region.
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http://dx.doi.org/10.1186/1472-6823-10-19 | DOI Listing |
Discov Oncol
December 2024
Department of Radiology, Addis Ababa University, Addis Ababa, Ethiopia.
Primary intracranial yolk sac tumor (YST) with orbital involvement is an exceedingly rare extragonadal germ cell tumor, with only a limited number of cases reported in the literature. Clinically, primary intracranial yolk sac tumor with orbital involvement may present with symptoms that mimic more common benign or malignant orbital disorders in children, potentially leading to diagnostic delays that can adversely impact survival. Diagnostic imaging modalities, including computed tomography (CT) and magnetic resonance imaging (MRI), are instrumental for assessing the tumor's size, precise localization, and extent.
View Article and Find Full Text PDFFront Oncol
November 2024
Beaumont Hospital, Beaumont Health, Royal Oak, MI, United States.
Papillary craniopharyngiomas are rare tumors prevalent to the precision oncology world due to their high rate of BRAF V600E mutations. Symptoms include vision loss, neuroendocrine dysfunction, and cognitive dysfunction. Treatment involves an interdisciplinary approach with surgery, radiation, and systemic treatment.
View Article and Find Full Text PDFCan J Ophthalmol
November 2024
University of Health Sciences, Basaksehir Cam and Sakura City Hospital, Department of Endocrinology and Metabolism, Istanbul, Turkey.
Objective: The aim of this study is to investigate the effects of preoperative parameters such as retinal nerve fiber layer (RNFL) thickness, visual acuity (VA), visual field (VF), and tumour volume on postoperative outcomes in patients with pituitary adenoma.
Design: Retrospective study.
Participants: Two-hundred and seventy-six eyes from 142 patients were included.
J Clin Neurosci
December 2024
Department of Neurosurgery, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India. Electronic address:
Surg Neurol Int
September 2024
Department of Neurosurgery, Salford Royal NHS Foundation Trust, Salford, United Kingdom.
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