AI Article Synopsis
- Cryotherapy is a noncontact method used to treat cancerous and precancerous conditions, notably dysplastic Barrett's esophagus.
- Liquid nitrogen and carbon dioxide are the primary substances used in this treatment, showing strong effectiveness and safety in reversing dysplastic mucosa.
- Ongoing research continues to explore the potential of cryotherapy for treating Barrett's esophagus.
Article Abstract
Cryotherapy is a noncontact ablation method that has long been used clinically in the treatment of a wide variety of malignant and premalignant diseases. The relative ease of use and unique mechanisms of cellular destruction make cryotherapy particularly attractive for the eradication of dysplastic Barrett's esophagus. Currently, liquid nitrogen and carbon dioxide are the most common cryogens used. Preliminary data with these agents have shown high efficacy in the reversal of dysplastic Barrett mucosa and excellent safety profiles. Intense investigation on cryotherapy ablation of Barrett's esophagus is ongoing.
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| http://dx.doi.org/10.1016/j.giec.2010.09.007 | DOI Listing |
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