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Effective identification of Alzheimer's disease in mouse models via deep learning and motion analysis.
Heliyon
December 2024
Department of Orthopaedics & Traumatology, School of Clinical Medicine, Li Kai Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Spatial disorientation is an early symptom of Alzheimer's disease (AD). Detecting this impairment effectively in animal models can provide valuable insights into the disease and reduce experimental burdens. We have developed a markerless motion analysis system (MMAS) using deep learning techniques for the Morris water maze test.
View Article and Find Full Text PDFSpatiotemporal understanding of behaviors of laying hens using wearable inertial sensors.
Poult Sci
December 2024
Institute of Engineering, Tokyo University of Agriculture and Technology, Tokyo 183-8538, Japan. Electronic address:
Automatic detection of behaviors and locations has been increasingly needed in the management of noncage systems where hen behaviors are highly diverse and active. Here we show a technology to spatiotemporally understand behaviors using a wearable inertial sensor, containing a 3-axis accelerometer and 3-axis angular velocity sensor (i.e.
View Article and Find Full Text PDFEffects of 16.8-22.0 T high static magnetic fields on the development of zebrafish in early fertilization.
Eur Radiol
November 2024
Institutes of Physical Science and Information Technology, Anhui University, Hefei, Anhui, P.R. China.
Objectives: Despite some existing studies on the safety of high static magnetic fields (SMFs), the effects of ultra-high SMFs above 20.0 T for embryonic development in early pregnancy are absent. The objective of this study is to evaluate the influence of 16.
View Article and Find Full Text PDFIntra and interspecific audience effect on domestic dogs' behavioural displays and facial expressions.
Sci Rep
April 2024
Domestication Lab, Konrad-Lorenz-Institute for Ethology, University of Veterinary Medicine, Veterinärplatz 1, 1210, Vienna, Austria.
The aim of the current study was to investigate the influence of both intra- and interspecific audiences on dogs' facial expressions and behaviours. Forty-six dogs were exposed to three test conditions in which a food reward, initially available, was denied when in the presence of either a human (Human condition) or a dog audience (Dog condition), or in the absence of a visible audience (Non-social condition). Salivary cortisol was collected to evaluate the stress/arousal activation in the different conditions.
View Article and Find Full Text PDFDexmedetomidine Sedation in Dogs: Impact on Electroencephalography, Behavior, Analgesia, and Antagonism with Atipamezole.
Vet Sci
February 2024
College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.
This study aimed to assess the impact of dexmedetomidine constant rate infusion (CRI) on key parameters in dogs. Six dogs received a 60 µg/kg/h dexmedetomidine infusion over 10 min, followed by three 15 min decremental CRIs (3, 2, and 1 µg/kg/h). A subsequent reversal phase employed 600 µg/kg/h atipamezole over 5 min.
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