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From Compression to Itch: Exploring the Link Between Nerve Compression and Neuropathic Pruritus.
Am J Clin Dermatol
October 2024
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
Article Synopsis
- * It often manifests in specific forms such as brachioradial pruritus in the forearms, notalgia paresthetica in the upper back, and anogenital itch, which can be related to spine problems.
- * Treatment may involve topical remedies or systemic medications, but currently, there are no FDA-approved options specifically for neuropathic itch, making it essential to understand its neural causes for effective management.
Orthopedic Dermatopathies: Skin Manifestations in Orthopedic Conditions.
J Orthop Sports Med
August 2024
Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California USA.
Orthopedic diseases often present with dermatological symptoms that require prompt identification for appropriate treatment. Understanding these dermatologic presentations is crucial for accurate diagnosis and effective management. This article critically reviewed the dermatological manifestations observed in general and regional pathologies, followed by treatment-related manifestations.
View Article and Find Full Text PDFTreatment of Brachioradial Pruritus: A Tertiary Center Retrospective Analysis.
Acta Derm Venereol
June 2024
Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, USA.
Article Synopsis
- This study compared the effectiveness of two treatment methods for relieving itch in patients with brachioradial pruritus: pregabalin alone vs. pregabalin combined with ketamine, amitriptyline, and lidocaine cream.
- Both treatment regimens showed significant reduction in itch scores, but there was no notable difference in effectiveness between the two groups.
- Some patients reported mild side effects, suggesting a need for personalized treatment plans, and further research is recommended for determining the best approaches to manage this condition.
Brachioradial Pruritus Caused by Cervical Disc Herniation Precipitated by Trauma Treated with Anterior Cervical Discectomy and Fusion: Report of Two Cases and Review of the Literature.
Asian J Neurosurg
March 2024
Tufts University School of Medicine, Boston, Massachusetts, United States.
Brachioradial pruritis (BRP) is a rare form of dermatomal pruritis that appears to be caused both by cervical radiculopathy and exposure to ultraviolet-light, although the exact pathophysiology for the manifestation of these symptoms remains to be determined. A diagnosis of BRP is typically confirmed with the "ice-pack" test and evidence of cervical spine pathology using magnetic resonance imaging. Treatment options consist of application of ice, reduction in sun exposure, and topical capsaicin, antiepileptics, or tricyclic antidepressants.
View Article and Find Full Text PDFAtypical cervical radiculopathy presenting with brachioradial pruritus: illustrative cases.
J Neurosurg Case Lessons
February 2024
2Division of Neurosurgery, Hoag Spine Institute, Hoag Hospital, Newport Beach, California.
Article Synopsis
- Brachioradial pruritus (BRP) is a rare chronic condition causing persistent itching, burning, or tingling, often linked to cervical radiculopathy.
- Two patients, a 44-year-old female and a 51-year-old male, experienced relief from BRP symptoms after undergoing surgery for atypical cervical radiculopathy.
- The findings suggest a connection between cervical spondylosis and BRP, emphasizing the effectiveness of surgical treatment for this condition.
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