Concurrence of Stevens-Johnson Syndrome and Bilateral Parotitis after Minocycline Therapy.

Case Rep Dermatol

Department of Dermatology, Institute of Health Sciences, School of Medicine, Gyeongsang National University Hospital, Jinju, Korea.

Published: June 2010

AI Article Synopsis

  • Minocycline is an antibiotic used primarily for treating moderate to severe acne and belongs to the tetracycline family.
  • Rare adverse reactions can occur, ranging from mild skin eruptions to severe conditions like drug-induced lupus and Stevens-Johnson syndrome.
  • The case study highlights a Korean boy who developed Stevens-Johnson syndrome and bilateral parotitis after taking minocycline, emphasizing the need for cautious use of this medication.

Article Abstract

Minocycline is an antibiotic of tetracycline derivatives that is commonly used in the treatment of moderate to severe acne vulgaris. It has been reported to cause rare adverse events from mild cutaneous eruption to severe forms including drug-induced lupus, serum sickness-like reaction, and hypersensitivity reactions, etc. The risks of adverse events attributed to minocycline have not been ascertained reliably and there are concerns about the safety of minocycline which could possibly result in life-threatening events such as the Stevens-Johnson syndrome. Here we demonstrate an unusual case of Stevens-Johnson syndrome in conjunction with bilateral parotitis after the intake of minocycline in a Korean boy suggesting discreet use of the drug.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988842PMC
http://dx.doi.org/10.1159/000314952DOI Listing

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