Purpose: Giant fornix syndrome is a chronic copiously purulent conjunctivitis seen in elderly patients with dehiscence of the levator palpebrae superioris aponeurosis. We report a case of giant fornix syndrome secondary to methicillin-resistant Staphylococcus aureus conjunctivitis that was recalcitrant to standard treatment modalities, and we describe 2 novel interventions for this condition, which succeeded in eradicating the infection.
Methods: Case report.
Results: After failing an aggressive treatment course of topical antibiotics and corticosteroids and after demonstrating an inability to tolerate oral antibiotics, the patient was treated with supratarsal subconjunctival injections of vancomycin and triamcinolone, followed by repeated sweepings of the conjunctival fornices with 10% povidone-iodine on a cotton swab. The patient's symptoms improved dramatically after the antibiotic and corticosteroid injections and ultimately resolved completely after multiple povidone-iodine sweepings.
Conclusions: In patients with giant fornix syndrome who are recalcitrant to or intolerant of aggressive topical and systemic therapy, supratarsal subconjunctival injections of antibiotics and corticosteroids and sweeping of the conjunctival fornices with povidone-iodine are 2 local treatments which may be useful in eradicating the infection.
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http://dx.doi.org/10.1097/ICO.0b013e3181eeb703 | DOI Listing |
Photodiagnosis Photodyn Ther
April 2024
Shanghai Skin Disease Hospital, School of Medicine, Institute of Photomedicine, Tongji University, 1278 Baode Road, Shanghai 200443, China. Electronic address:
Photodynamic therapy (PDT) is proved effective for treating low-grade squamous intraepithelial lesions (LSIL) and condylomata acuminata (CA). 5-Aminolevulinicacid (5-ALA) is the most common applied photosensitizer, but high rate of unbearable pain and relative long incubation time were reported. Here, we report a 27-year-old woman suffering from cervical and vaginal giant CA with LSIL involving the whole right vaginal fornix, cervical surface, and vaginal wall.
View Article and Find Full Text PDFGMS Ophthalmol Cases
September 2023
Pathology Department, Gobind Ballabh Pant Institute of Post Graduate Medical Education & Research, New Delhi, India.
Purpose: To report the case of an extremely large overhanging bleb, extending from superior fornix to limbus, in a 57-year-old poorly controlled diabetic, six years after trabeculectomy for an uncontrolled primary open angle glaucoma (POAG) with recurrence, months after complete excision.
Methods: An overhanging bleb is defined as a filtering cicatrix which has been massaged downward over the cornea by eyelid action. It has been linked to anti-metabolite use during glaucoma filtering surgery.
Childs Nerv Syst
April 2023
Neurosurgery Department, Garrahan Hospital, Buenos Aires, Argentina.
Introduction: Choroidal fissure cysts (CFC) are usually an incidental finding on imaging and lead to morbidity only in rare cases. The aim of this study was to present the case of a patient with a giant CFC and its treatment.
Case Report: The patient was a male infant of 9 days of life that presented with symptoms of intracranial hypertension.
J Stroke Cerebrovasc Dis
October 2022
Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT, United State. Electronic address:
Background: Diagnosis of giant cell arteritis has traditionally relied on demonstration of pathologic changes on temporal artery biopsy.
Method: To highlight recent advances in large vessel imaging resulting in revised diagnostic criteria for giant cell arteritis.
Conclusion: We call attention to the revised diagnostic criteria imaging evidence of extracranial large vessel thickening as an alternative to temporal artery biopsy in diagnosis of giant cell arteritis in a patient with heralding anterior fornix infarct.
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