Objective: To discuss the possible mechanism of drug resistance transmission between Staphylococcus and Escherichia coli.
Methods: The chloramphenicol resistance plasmid of Staphylococcus aureus was extracted to transform the sensitive Escherichia coli, and the drug-resistant Escherichia coli were screened by drug sensitivity test.
Results: The drug-resistant Escherichia coli were successfully obtained.
Conclusion: Staphylococcus may have a natural shuttle plasmid of drug resistance, which can transform Escherichia coli under specific conditions.
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