Bone is a strongly heterogeneous natural composite with microstructure. Although the classical theory of linear elasticity has been largely used in bone ultrasonic studies, it cannot sufficiently describe the mechanical behavior of materials with microstructure. Furthermore, this theory predicts non-dispersive behavior of Rayleigh waves, which is in conflict with experimental observations. By using the simplest theory of gradient elasticity we recently demonstrated that bone's microstructure significantly affects the dispersion of classical Lamb modes. In this work, we investigate the effect of bone's microstructure on the propagation of Rayleigh waves by using the Boundary Element Method (BEM). We assume an isotropic semi-infinite space with mechanical properties equal to those of bone and microstructure. Microstructural effects are taken into account by introducing in the stress analysis the internal length scale parameters l(1), l(2), h(1), h(2). BEM computations are performed for various combinations of these parameters with values empirically chosen close to the osteon's size. The constants' values are also compared to those derived from closed form relations. The results made clear that bone's microstructure significantly affects Rayleigh wave dispersion.
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http://dx.doi.org/10.1109/IEMBS.2010.5627756 | DOI Listing |
J Anat
January 2025
Museo Argentino de Ciencias Naturales "Bernardino Rivadavia", CONICET, Buenos Aires, Argentina.
Notosuchia were a successful lineage of Crocodyliformes that achieved a remarkable diversity during the Cretaceous of Gondwana, particularly in South America. Although paleohistology has expanded our knowledge of the paleobiology of notosuchians, several clades of this lineage remain poorly understood in this aspect. Here we help to address this gap by conducting the first histological analysis of appendicular bones of a peirosaurid.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, The People's Republic of China.
Objectives: The incidence rate of intervertebral disc degeneration (IVDD) is increasing year by year, which brings great harm to our health. The change of biomechanical factors is an important reason for IVDD. Therefore, more and more studies use finite element (FE) models to analyze the biomechanics of spine.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Department of Industrial Engineering, Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Introduction: Bone spinal metastases disrupt the bone homeostasis, inducing a local imbalance in the bone formation and/or resorption, with consequent loss of the structural optimisation of the vertebrae and increase of the risk of fracture. Little is known about the microstructure of the metastatic tissue, the microstructure of the tissue surrounding the lesion, and how it does compare with vertebrae with no lesions observed on the biomedical images. A comprehensive assessment of the microstructural properties of the entire vertebral body can be obtained with micro computed tomography.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg- Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
Background: In atlantoaxial instabilities, posterior C1/C2 fusion using lateral mass screws (LMS) or pedicle screws (PS) in a mono- or bicortical position in the atlas is a typical treatment. The bone microstructure and positioning of the screw trajectories appear to be of significant relevance for stability.
Purpose: The aim of this study was a comparative analysis of the mechanical durability of screw fixation concerning microstructural characteristics of the trajectories of LMS and PS in mono- and bicortical position.
Although the toxic effect of Sedentary behavior (SED) on bone health has been demonstrated in the previous study, the underlying mechanisms of SED, or break SED to bone health remain unclear. In this study, we aim to investigate the effects of sedentary behavior (SED) on bone health, as well as the potential favor effects of moderate to vigorous physical activity (MVPA) and periodic interruptions of SED. To simulate SED, we used small Plexiglas cages (20.
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