Megavoltage photon sources are normally used for radiotherapy treatments. For these equipments an accurate knowledge of their spectral distribution is essential for accurate dose calculations planning. There are several ways to determine the spectrum of a clinical photon beam: direct measurement, electron source modelling or reconstruction from experimental measures. In this paper we focus on the latter type of spectral reconstruction methods which can be used to provide an independent confirmation of source models for a given machine without any prior knowledge of the spectral distribution. This technique involves measuring the depth dose curve in a water phantom and applying an unfolding method using Monte Carlo simulated depth dose curves for consecutives mono-energetic beams. We illustrate this theory to calculate a 6 MeV photon beam from an Elekta Precise radiotherapy unit using the gradient of depth dose measurements in a cube-shaped water tank.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1109/IEMBS.2010.5626399 | DOI Listing |
Am J Vet Res
January 2025
Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA.
Objective: To evaluate the sparing effects of fentanyl and maropitant on sevoflurane minimum alveolar concentrations that block autonomic responses (MACBAR) and the hemodynamic and electroencephalographic responses to noxious stimuli in dogs.
Methods: The sevoflurane MACBAR was determined in 5 healthy male Beagles with or without continuous infusions of fentanyl and maropitant. Then, intermittent noxious stimulation was applied at 1.
Phys Med Biol
January 2025
Radiotherapy and Radiation Dosimetry group, National Physical Laboratory, Hampton Road, Middlesex, Teddington, TW11 0LW, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
Internationally, reference dosimetry for clinical proton beams largely follows the guidelines published by the International Atomic Energy Agency (IAEA TRS-398 Rev. 1, 2024). This approach yields a relative standard uncertainty of 1.
View Article and Find Full Text PDFEur Thyroid J
January 2025
F Langhauser, Neurology, University Hospital Essen Department of Neurology, Essen, Germany.
Objective Thyroid hormones (TH) control a variety of processes in the central nervous system and influence its response to different stimuli, such as ischemic stroke. Post-stroke administration of 3,3',5-triiodo-L-thyronine (T3) has been reported to substantially improve outcomes, but the optimal dosage and time window remain elusive. Methods Stroke was induced in mice by transient middle cerebral artery occlusion (tMCAO) and T3 was administered at different doses and time points before and after stroke.
View Article and Find Full Text PDFEnviron Toxicol Chem
January 2025
Centro di Referenza Nazionale per l'Analisi e Studio di Correlazione tra Ambiente, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Portici, Italy.
A statistical procedure has been developed to derive a screening value from an observational study related to the developmental toxicity observed in loggerhead turtle (Caretta caretta) eggs exposed to long chain per- and polyfluoroalkyl substances (PFAS). A dataset of 41 nests in which the hatching rate was inversely correlated with the increase in the PFAS concentration in unhatched eggs was processed via a categorical regression approach. After outliers identification and removal, categorical regression analysis tested the relationships of the outcomes with the following parameters: perfluoro-nonanoic (PFNA), decanoic (PFDA), undecanoic (PFUdA), and dodecanoic (PFDoA) acids; perfluoroctansulfonate (PFOS); polychlorobiphenyls (PCBs) 28, 52, 101, 138, 153, 180; lead (Pb), total mercury (Hgtot), and cadmium (Cd); and other factors, such as "nest site," "clutch size," "incubation duration," and "nest minimum depth," as confounders/modifiers of the hatching rate.
View Article and Find Full Text PDFVet Radiol Ultrasound
January 2025
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri, USA.
Strontium-90 plesiotherapy delivers high doses of radiation to superficial lesions (<3 mm depth) with excellent sparing of deeper tissues. The sealed-source applicator tip is circular and 8-10 mm in diameter. Larger treatment fields are treated with multiple overlapping fields.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!