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Xanthogranulomatous pyelonephritis with unconnected liver lesion. | LitMetric

Xanthogranulomatous pyelonephritis with unconnected liver lesion.

Urology

Department of Pediatric Surgery, Inonu University, Faculty of Medicine, Turgut Ozal Medical Center, Malatya, Turkey.

Published: July 2011

AI Article Synopsis

  • Xanthogranulomatous pyelonephritis is a rare chronic kidney inflammation that results in tissue destruction and replacement with granulomatous tissue, primarily affecting adults and rarely seen in children.
  • A case was reported involving a 5-month-old boy who had a left renal and liver mass, initially misdiagnosed as Wilms' tumor, leading to a total nephrectomy and liver biopsy.
  • Histopathological analysis ultimately revealed that both masses were due to xanthogranulomatous pyelonephritis, highlighting the need for increased awareness of this condition to improve preoperative diagnosis, even when other tissue lesions are present.

Article Abstract

Xanthogranulomatous pyelonephritis is a chronic renal inflammation characterized by destruction and replacement of its parenchyma with granulomatous tissue. This uncommon condition is rare in children. We report on a 5-month-old male infant with a left renal and hepatic mass detected by ultrasound. The case was preoperatively misdiagnosed as Wilms' tumor and total nephrectomy and biopsy from liver lesion were performed. The subsequent histopathological findings confirmed the diagnosis of xanthogranulomatous pyelonephritis for renal and liver lesions. Increasing awareness of this disease should lead to the diagnosis being suspected preoperatively even if it is with unconnected tissue lesions.

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Source
http://dx.doi.org/10.1016/j.urology.2010.08.042DOI Listing

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