Article Title And Bibliographic Information: Salivary glucose levels and oral candidal carriage in type II diabetics. Sashikumar R, Kannan R. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;109(5):706-11.
Reviewer: Wenche S. Borgnakke, DDS, MPH, PhD.
Purpose/question: (1) What is the relationship between salivary glucose and oral candida carriage? and (2) Can salivary glucose levels be used to monitor diabetes control?
Source Of Funding: The Chennai Dental Research Foundation, India.
Type Of Study/design: Cross-sectional
Level Of Evidence: Level 2: Limited-quality, patient-oriented evidence.
Strength Of Recommendation Grade: Not applicable.
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http://dx.doi.org/10.1016/j.jebdp.2010.09.018 | DOI Listing |
Int J Pharm
January 2025
Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM'S NMIMS, V. L. Mehta Road, Vile Parle (W), Mumbai, India. Electronic address:
Diabetes is a disorder attributed to impaired production or utilization of insulin and requires rapid precise monitoring of glucose levels. The fabrication of nanotechnology-based non-invasive biosensors for glucose detection holds significant promise for improved diabetes care and point-of-care diagnostics. The study demonstrates a novel molecularly imprinted polymers (ADMIPs) based sensitive biosensor for glucose estimation in saliva using three distinct sensing platforms -cotton swab, paper strip and polymeric film by colorimetric assay.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Medicine, SUNY at Buffalo School of Medicine, Buffalo, NY, USA.
Sjögren's (SS) involves salivary and lacrimal gland dysfunction. These studies examined metabolic profiles in the B6. transgene mouse model of SS and a cohort of human SS patients at different stages of disease.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Conservative Dentistry, Faculty of Dentistry, University of Chile, Santiago 9170022, Chile.
: Oral biomarkers have gained attention as non-invasive tools for assessing systemic diseases due to their potential to reflect physiological and pathological conditions. This review aims to explore the role of oral biomarkers in diagnosing and monitoring systemic diseases, emphasizing their diagnostic relevance and predictive capabilities in clinical practice. : This narrative review synthesizes the current literature on biochemical, immunological, genetic, and microbiological oral biomarkers, with a focus on their sources, types, and clinical applications.
View Article and Find Full Text PDFMicrobiome
January 2025
Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Blegdamsvej 3B, Copenhagen, 2200, Denmark.
Background: Saliva is a protein-rich body fluid for noninvasive discovery of biomolecules, containing both human and microbial components, associated with various chronic diseases. Type-2 diabetes (T2D) imposes a significant health and socio-economic burden. Prior research on T2D salivary microbiome utilized methods such as metagenomics, metatranscriptomics, 16S rRNA sequencing, and low-throughput proteomics.
View Article and Find Full Text PDFIran J Public Health
December 2024
Medical Department, Chongqing Hospital of Traditional Chinese Medicine, Chongqing 400021, China.
Background: Salivary compounds can be used as diagnostic markers for changes in the oral cavity that cause oral problems in type 2 diabetes mellitus (T2DM).
Methods: This meta-analysis searched PubMed/Medline, EMBASE, Scopus and Cochrane Library, and the Web of Science until Nov 2023. The observational studies included patients with T2DM and healthy controls aged > 18 yr with no oral health problems or systematic or periodontal diseases.
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