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A rare and challenging case of amelanotic subungual melanoma from Syria.
Melanoma Manag
December 2024
Department of Plastic Surgery, Faculty of Medicine, University of Aleppo, Aleppo, Syria.
Subungual melanoma accounts for 1.9% of cutaneous melanomas. Amelanotic cases, comprising 15-25%, poses a significant diagnostic challenge because it can be misdiagnosed as other traumatic, inflammatory, or neoplastic conditions.
View Article and Find Full Text PDFPlantar acral melanoma: epidemiological, clinical, dermoscopic and histopathological features. A Brazilian cohort.
An Bras Dermatol
January 2025
Department of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil; Dermatology Unity, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Background: Acral melanomas (AM) are rare and approximately two-thirds of them occur on the soles of the feet beeing more prevalent in black and Asian individuals. Data on this subtype of melanoma are scarce in the Brazilian population.
Objectives: To describe and correlate the epidemiological, clinical, dermoscopic, and histopathological features of AM a.
Cyclin-Dependent Kinase Inhibitors in the Rare Subtypes of Melanoma Therapy.
Molecules
November 2024
Department of Histology and Embryology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-067 Bydgoszcz, Poland.
Melanoma occurs in various forms and body areas, not only in the cutis, but also in mucous membranes and the uvea. Rarer subtypes of that cancer differ in genomic aberrations, which cause their minor sensibility to regular cutaneous melanoma therapies. Therefore, it is essential to discover new strategies for treating rare forms of melanoma.
View Article and Find Full Text PDFThe Application of Mohs Micrographic Surgery in the Treatment of Acral Basal Cell Carcinoma: A Report of Two Cases.
J Clin Med
November 2024
Dr. Leventer Centre, 011216 Bucharest, Romania.
Mohs micrographic surgery (MMS) is a precise skin surgery technique that is particularly useful in the treatment of high-risk skin cancers and tumors located in challenging anatomical areas. we report two cases of basal cell carcinoma located in the acral areas effectively treated using MMS. the presented cases demonstrate that MMS is an excellent surgical modality providing outstanding medical, cosmetic, and functional outcomes.
View Article and Find Full Text PDFSocial vulnerabilities in head-neck melanoma care: A retrospective cohort study in the United States.
JAAD Int
December 2024
Department of Otolaryngology-Head and Neck Surgery, University of Tennessee Health Science Center, Memphis, Tennessee.
Article Synopsis
- This study examines how various social determinants of health (SDH), not just socioeconomic factors, impact the management of head-neck melanomas (HNM) in the U.S. using the Social Vulnerability Index (SVI).
- It analyzed data from over 374,000 adults diagnosed with HNM from 1975 to 2017, revealing that higher social vulnerability is linked to reduced surgical options, increased likelihood of radiation treatment, and more advanced disease at diagnosis.
- Key findings indicate that household composition, socioeconomic status, and minority-language status significantly influence disparities in HNM management, despite limitations like unknown causes of death and reliance on county-level SVI calculations.
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