Annual report of the Australian National Poliovirus Reference Laboratory, 2009.

Commun Dis Intell Q Rep

National Poliovirus Reference Laboratory, Victorian Infectious Diseases Reference Laboratory, North Melbourne, Victoria.

Published: September 2010

AI Article Synopsis

  • The Australian National Poliovirus Reference Laboratory (NPRL) conducts testing on faecal specimens from acute flaccid paralysis (AFP) cases, working as a key poliovirus reference center for the Western Pacific Region, in line with WHO recommendations.
  • In 2009, Australia reported a non-polio AFP rate of 1.17 cases per 100,000 children under 15, with only 33.3% of the classified cases providing adequate faecal samples as required by WHO guidelines.
  • The laboratory identified a Sabin-like poliovirus from a non-AFP case, highlighting a potential importation since Australia stopped using the Sabin oral polio vaccine in 2005, while wild poliovirus remains endemic in some

Article Abstract

The Australian National Poliovirus Reference Laboratory (NPRL) is accredited by the World Health Organization (WHO) for the testing of faecal specimens from acute flaccid paralysis (AFP) cases and operates as a regional poliovirus reference laboratory for the Western Pacific Region. The NPRL, in collaboration with the Australian Paediatric Surveillance Unit, co-ordinates surveillance for cases of AFP in children in Australia, according to criteria recommended by the WHO. Specimens are referred from AFP cases in children and suspected cases of poliomyelitis in persons of any age. The WHO AFP surveillance performance indicator is 1 non-polio AFP case per 100,000 children less than 15 years of age. In 2009, the Polio Expert Committee classified 48 cases as non-polio AFP, a rate of 1.17 cases per 100,000 children less than 15 years of age. An additional WHO AFP surveillance performance indicator is that more than 80% of notified AFP cases have 2 faecal samples collected 24 hours apart and within 14 days of onset of paralysis. Adequate faecal samples were received from 16 (33.3%) of the 48 classified cases. A poliovirus was referred via the Enterovirus Reference Laboratory Network of Australia from a non-AFP case and was determined to be Sabin-like. This case most likely represents an importation event, the source of which was not identified, as Australia ceased using Sabin oral polio vaccine in 2005. The last report of a wild poliovirus importation in Australia was from Pakistan in 2007. In 2009, 1,604 wild poliovirus cases were reported in 23 countries with Afghanistan, India, Nigeria and Pakistan remaining endemic for poliomyelitis.

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