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Similar Publications

Backstage Heroes-Yeast in COVID-19 Research.

Int J Mol Sci

November 2024

Department of Bioenergetics, Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University, 61-614 Poznań, Poland.

The extremely rapid development of understanding and technology that led to the containment of the COVID-19 pandemic resulted from collaborative efforts in the fields of (SARS-CoV-2) biology, pharmacology, vaccinology, and medicine. Perhaps surprisingly, much of the research was conducted using simple and efficient yeast models. In this manuscript, we describe how yeast, eukaryotic microorganisms, have been used to research this global challenge, focusing on the therapeutic potential of the studies discussed herein.

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RAND researchers present findings from the qualitative arm of the research project, sharing insights from interviews with U.S. military and veteran caregivers.

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Background: Schizophrenia is a complex mental health disorder that not only affects the individual diagnosed but also has profound implications for their families and caregivers. This paper aims to shed light on the emotional, social and practical challenges faced by caregivers, as well as the coping mechanisms they employ to navigate the complexities of caregiving.

Methods: Through semi-structured interviews with caregivers of patients with schizophrenia, thematic analysis was employed to uncover the initial reactions, dynamics, daily life impact and coping skills.

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The COVID-19 pandemic posed significant challenges to global health and raised important questions about social coordination. Amidst the crisis, discursive constructions of national heroes proliferated in Chinese and U.S.

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Engineering and targeting potential of CAR NK cells in colorectal cancer.

Chin Med J (Engl)

November 2024

Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu 225009, China.

Colorectal cancer (CRC), a major global health concern, necessitates innovative treatments. Chimeric antigen receptor (CAR) T cells have shown promise, yet they grapple with challenges. The spotlight pivots to the rising heroes: CAR natural killer (NK) cells, offering advantages such as higher safety profiles, cost-effectiveness, and efficacy against solid tumors.

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