CryoTEM demonstrates that a CNA35-bearing liposomal MRI contrast agent selectively binds to poorly assembled collagen type I as opposed to well-assembled collagen fibrils, whereas monomeric CNA35 binds to all forms of collagen. It is shown that upon conjugation to liposomes and micelles CNA35 loses its ability to dissociate ordered collagen fibrils and thereby to create its own binding sites.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c0cc02901g | DOI Listing |
Publication Analysis
Top Keywords
collagen fibrils
12
collagen
5
binding cna35
4
cna35 contrast
4
contrast agents
4
agents collagen
4
fibrils cryotem
4
cryotem demonstrates
4
demonstrates cna35-bearing
4
cna35-bearing liposomal
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!