The Calibration and Validation Group (CVG) was founded in early 1995 by Herman Lam, Chung Chow Chan and YC Lee in Toronto, Canada. At that time, the requirements and the practices of method validation, analytical system qualification and instrument performance verification were only discussed individually among a very small group of professionals; the founders realized that there was a need to form a scientific organization to focus on those subjects and share the learning. Initially, the membership was mainly derived from the regulated pharmaceutical industry, but the participation has grown over the years to include scientists from a wide range of backgrounds, including pharmaceuticals, chemicals, environmental, food, distilleries, biotechnology, instrument vendors, government agencies, local colleges and universities. CVG was officially incorporated as a nonprofit organization in Canada in 1999.
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http://dx.doi.org/10.4155/bio.09.36 | DOI Listing |
Sci Rep
January 2025
Department of Gastroenterology, Jiangxi Provincial Key Laboratory of Digestive Diseases, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Fever is a complication after colorectal endoscopic submucosal dissection (ESD). The objective of this study was to explore the incidence and risk factors of fever after colorectal ESD and establish a predictive nomogram model. This retrospective analysis encompassed patients with colorectal lesions who underwent ESD between June 2008 and December 2021 in our center.
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January 2025
Department of Rheumatology and Immunology, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.
Developing a new diagnostic prediction model for osteoarthritis (OA) to assess the likelihood of individuals developing OA is crucial for the timely identification of potential populations of OA. This allows for further diagnosis and intervention, which is significant for improving patient prognosis. Based on the NHANES for the periods of 2011-2012, 2013-2014, and 2015-2016, the study involved 11,366 participants, of whom 1,434 reported a diagnosis of OA.
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January 2025
ETH Zürich, Institut für Umweltingenieurwissenschaften, Zürich, Switzerland.
Mangrove forests thrive along global tropical coasts, acting as a barrier that protects coastlines against storm surges and as nurseries for an entire food web. They are also known for their high carbon sequestration rates and soil carbon stocks. We introduce a new global mangrove canopy height map generated from TanDEM-X spaceborne elevation measurements collected during the 2011-2013 period with a 12-meter spatial resolution and an accuracy of 2.
View Article and Find Full Text PDFBMC Musculoskelet Disord
January 2025
Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada.
Background: To summarize the statistical performance of machine learning in predicting revision, secondary knee injury, or reoperations following anterior cruciate ligament reconstruction (ACLR), and to provide a general overview of the statistical performance of these models.
Methods: Three online databases (PubMed, MEDLINE, EMBASE) were searched from database inception to February 6, 2024, to identify literature on the use of machine learning to predict revision, secondary knee injury (e.g.
BMC Pediatr
January 2025
Department of Pediatrics, Qilu Hospital, Shandong University, No.107, West Culture Road, Lixia District, Jinan City, Shandong Province, 250000, China.
Background: Purulent meningitis (PM) is a commonly encountered infectious condition in newborns, which unfortunately can result in infant mortality. Newborns with PM often present nonspecific symptoms. The success of lumbar puncture, an invasive test, relies on the operator's expertise.
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