A series of dihydropyridines were identified that have an effect on the accumulation of tau, an important target in Alzheimer's disease. The dihydropyridine collection was expanded using the Hantzsch multicomponent reaction to develop preliminary structure-activity relationships.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251959 | PMC |
| http://dx.doi.org/10.1039/c0cc02253e | DOI Listing |
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