AI Article Synopsis
- The rise of multidrug-resistant Shigella strains is becoming a significant global health issue.
- Third-generation cephalosporins are typically used to treat these infections, but resistance has developed due to extended-spectrum ß-lactamases.
- This report presents a case of extended-spectrum ß-lactamase producing Shigella flexneri found in an 8-year-old girl in Pakistan, highlighting a new concern in the region.
Article Abstract
Emergence of multidrug-resistant strains of Shigella is a growing concern across the globe. Third-generation cephalosporins are used for treating infections caused by multidrug-resistant Shigellae. However, resistance to these cephalosporin antibiotics due to extended-spectrum ß-lactamases, has emerged as a new problem. So far extended-spectrum ß-lactamases producing Shigella has not been reported from Pakistan. We report such a case in Shigella flexneri from an 8-year old girl with acute dysentery.
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