Advances in laser technology now permit the physician to provide an effective form of treatment for a variety of cutaneous disorders for which no previous therapy existed. Additional refinements in both laser instruments and treatment techniques are certain to have a profound impact on the treatment of skin lesions. For that reason, a complete understanding of the basic properties of lasers and how they can be utilized in various clinical settings is the goal of this article.
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Study on the efficacy of fractional CO laser treatment for vaginal relaxation syndrome combined with recurrent bacterial vaginitis.
Sci Rep
January 2025
Department of Gynecology, Guilin People's Hospital, Guilin, 541002, China.
To investigate the efficacy and mechanisms of fractional CO2 laser treatment for Vaginal Relaxation Syndrome (VRS) combined with recurrent bacterial vaginitis. Patients with VRS and recurrent bacterial vaginitis were randomly assigned to an intervention group (n = 60) receiving fractional CO2 laser therapy in addition to metronidazole, or a control group (n = 60) receiving metronidazole alone. Post-treatment assessments included vaginal relaxation, vaginal health index (VHI) scores, lactobacilli distribution, vaginal pH, recurrence rates, and the correlation between lactobacilli distribution and VHI.
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Sci Rep
January 2025
Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse, 3010, Bern, Switzerland.
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View Article and Find Full Text PDFSingle cell combined with laser ablation ICP-MS to study cisplatinum (IV) loaded nanoparticles penetration pathways in osteosarcoma spheroids.
Anal Chim Acta
January 2025
Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo. C/ Julián Clavería 8, 33006, Oviedo, Spain; Health Research Institute of Asturias (ISPA), Avda de Roma s/n, 33011, Oviedo, Spain. Electronic address:
Background: 3D cellular structures have been considered the following step in the evaluation of drugs penetration after 2D cultures since they are more physiologically representative in cancer cell biology. Here the penetration capabilities of Pt (IV)-loaded ultrasmall iron oxide nanoparticles in 143B osteosarcoma multicellular spheroids of different sizes is conducted by a multidimensional quantitative approach. Single cell (SC) and imaging techniques (laser ablation, LA) coupled to inductively coupled plasma-mass spectrometry (ICP-MS) are used to visualize their penetration pathways and distribution in comparison to those of cisplatin.
View Article and Find Full Text PDFEfficacy of laser therapy on primary burning mouth syndrome: a systematic review.
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Department of Dental Medicine, Fattouma Bourguiba University Hospital of Monastir, 5000 Monastir, Tunisia.
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View Article and Find Full Text PDFHome-based rehabilitation versus centre-based programs in patients with temporomandibular disorders-a systematic review and meta-analysis.
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College of Sports Medicine and Physical Therapy, Beijing Sport University, 100084 Beijing, China.
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