Our ability to dissect and understand the principles of gene regulatory circuits is partly limited by the resolution of our experimental assays. In this brief review, we discuss aspects of gene expression in microbial organisms apparent only when increasing the experimental resolution from populations to single cells and sub-cellular structures, from snap-shots to high-speed time-lapse movies and from molecular ensembles to single molecules.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.copbio.2010.10.004 | DOI Listing |
Publication Analysis
Top Keywords
single cells
8
studying transcriptional
4
transcriptional interactions
4
interactions single
4
cells sufficient
4
sufficient resolution
4
resolution ability
4
ability dissect
4
dissect understand
4
understand principles
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!