CCN5 is one of six proteins in the CCN family. This family of proteins has been shown to play important roles in many processes, including proliferation, migration, adhesion, extracellular matrix regulation, angiogenesis, tumorigenesis, fibrosis, and implantation. In this review, we focus on the biological and putative pathophysiological roles of CCN5. This intriguing protein is structurally unique among the CCN family members, and has a unique biological activity profile as well.
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http://dx.doi.org/10.1007/s12079-010-0098-7 | DOI Listing |
J Cell Commun Signal
December 2024
International CCN Society Nice France.
CNS Neurosci Ther
December 2024
Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, Shandong, China.
Background: The presence of glioma stem cells (GSCs) and the occurrence of mesenchymal phenotype transition contribute to the miserable prognosis of glioblastoma (GBM). Cellular communication network factor 1 (CCN1) is upregulated within various malignancies and associated with cancer development and progression, while the implications of CCN1 in the phenotype transition and tumorigenicity of GSCs remain unclear.
Methods: Data for bioinformatic analysis were obtained from The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) databases.
J Cell Commun Signal
September 2024
The present manuscript reports on the progress made toward the official announcement of the first World Conference on Cellular Communication and Signaling. This conference is made possible by the Association for research on biosignaling and communication initiative, which was originally launched in 2020 and revitalized during the 12th International Workshop on the Cell Communication Network family of genes in Oslo (June 20-23, 2024). The aim of this conference is to facilitate interactions among the members of societies interested in all aspects of research on Biosignaling and Communication.
View Article and Find Full Text PDFJ Cell Commun Signal
September 2024
International CCN Society Nice France.
The 12th international workshop on the CCN family of genes took place at the Scandic Holmenkollen Park Hotel in Oslo, Norway from June 20-23, 2024. In 2024, it was the second time, following the Nice meeting in 2022, that the scientific topics were expanded to include additional cellular signaling and communication pathways of interest to the CCN Society members, as suggested by Bernard Perbal in 2019. The 12th international CCN workshop, organized by Håvard Attramadal and Vivi T.
View Article and Find Full Text PDFDiscov Oncol
November 2024
Department of Radiation Oncology, Peking University Shenzhen Hospital, 1120 Lianhua Road, Shenzhen, 518036, Guangdong, China.
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