AI Article Synopsis
- The study aimed to evaluate small hepatic lesions detected by CT in patients with hepatocellular carcinoma (HCC) to determine if they are indeed HCC.
- Out of 74 small lesions analyzed, a significant number were confirmed as HCC, highlighting the limitations of traditional CT scans in diagnosing small tumors.
- The findings suggest that using CTAP and CTHA is beneficial for staging HCC, particularly when the primary tumor is larger than 30 mm, indicating a potential link between tumor size and additional small lesions.
Article Abstract
Purpose: Hepatic lesions identified by computed tomography (CT) during arterial portography (CTAP) or CT hepatic arteriography (CTHA) in hepatocellular carcinoma (HCC) patients are sometimes too small to be diagnosed as HCC. We undertook this cohort study to assess whether these small lesions are actually HCC, and to clarify the effectiveness of these imaging examinations in a clinical setting.
Methods: We assessed the characteristics of 74 tiny lesions detected by CTAP and/or CTHA, but not by CT in 67 patients.
Results: Seven out of 10 nodules were histologically confirmed as HCC and 18 out of 64 lesions increased in size and showed typical findings of HCC during the follow-up period. Multivariate analysis revealed that the size of the main tumor (>30 mm in diameter) was associated with the presence of tiny additional HCC lesions (P = 0.002).
Conclusions: These findings indicate that CTAP and CTHA are recommended for determining the stage of HCC, especially when the HCC nodule is larger than 30 mm in diameter.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939997 | PMC |
| http://dx.doi.org/10.1007/s12072-010-9190-6 | DOI Listing |
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