AI Article Synopsis
- The plateau pika, an underground mammal from the Tibetan plateau, has been studied using a set of 10 genetic markers (microsatellites) to determine parentage.
- Validation tests showed extremely low error rates in identifying parentage, with high power of discrimination and exclusion, indicating that the markers are very reliable.
- This genetic tool allows researchers to accurately assign offspring to mothers and identify fathers or relatives, making it useful for various studies on plateau pika populations.
Article Abstract
Background: The plateau pika (Ochotona curzoniae) is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigree were used to validate the power of this set of markers.
Results: The error in parentage assignment using a combination of these 10 loci was very low as indicated by their power of discrimination (0.803 - 0.932), power of exclusion (0.351 - 0.887), and an effectiveness of the combined probability of exclusion in parentage assignment of 99.999%.
Conclusion: All the offspring of a family could be assigned to their biological mother; and their father or relatives could also be identified. This set of markers therefore provides a powerful and efficient tool for parentage assignment and other population analyses in the plateau pika.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994782 | PMC |
| http://dx.doi.org/10.1186/1471-2156-11-101 | DOI Listing |
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