Varicocele is still an enigma. Its effects on semen analysis, fertility and, more recently, early ejaculation and spontaneous abortion in spouses are not yet fully understood. In this retrospective study, we evaluated these four parameters (semen analysis, fertility, early ejaculation and spontaneous abortion among spouses) in relation to varicocele and varicocelectomy during a 13-year period. A total of 1,711 patients with varicocele underwent varicocelectomy by high inguinal method (251 cases), subinguinal method (1,375 cases), scrotal method (34 cases), and subinguinal method with local anesthesia (38 cases). Our complication rate was acceptable. Sperm count, motility and morphology increased three months post operation in 55, 51, and 46%, respectively (P value 0.000, 0.000, and 0.015, respectively). Paternity was 56% after one year of post varicocelectomy follow-up. Only 7 out of 82 azoospermic men had sperm in their semen after varicocelectomy and only one of them with mild spermatogenic hypoplasia became a father. The spontaneous abortion rate in the spouses of respondents was 59%. Early ejaculation improved in 75% of the respondents. In conclusion, varicocelectomy does not improve sperm parameters in all men, but it improves pregnancy rate, early ejaculation, and scrotal pain.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Pubertal stress accelerates copulation in adult male rats: Mitigating effects of a high-calorie diet in adulthood.
Physiol Behav
December 2024
Instituto de Investigaciones Cerebrales, Universidad Veracruzana, Avenida Luis Castelazo s/n Col. Industrial Ánimas, Xalapa, Veracruz C. P. 91190. Mexico.
The pubertal phase involves significant brain reorganization, where external stressors and diet can profoundly influence long-term behavioral outcomes. In this study, we investigated the interaction between acute pubertal stress (via immune challenge) and a hypercaloric diet in adulthood on the copulatory sexual behavior of male Wistar rats. At postnatal day (PND) 35, pubertal males received a single injection of lipopolysaccharide (LPS, 1.
View Article and Find Full Text PDFIndependent factors associated with intracytoplasmic sperm injection outcomes in patients with complete azoospermia factor c microdeletions.
Hum Reprod Open
November 2024
Department of Urology, Peking University Third Hospital, Beijing, China.
Study Question: Which independent factors influence ICSI outcomes in patients with complete azoospermia factor c (AZFc) microdeletions?
Summary Answer: In patients with complete AZFc microdeletions, the sperm source, male LH, the type of infertility in women, and maternal age are the independent factors associated with ICSI outcomes.
What Is Known Already: AZF microdeletions are the second most prevalent factor contributing to infertility in men, with AZFc microdeletions being the most frequently affected locus, accounting for 60-70% of all cases. The primary clinical phenotypes are oligoasthenozoospermia and azoospermia in patients with complete AZFc microdeletions.
Computational and binding studies of the redesigned pentoxifylline analogue against phosphodiesterases function in sperm.
J Biomol Struct Dyn
December 2024
Macromolecular Structural Biology Lab, Department of Biotechnology, Indian Institute of Technology Hyderabad, Telangana, India.
Pentoxifylline (PTX) is a widely used pharmacological agent for the selection of motile sperm in both normozoospermic and asthenozoospermic ejaculates prior to their use in assisted reproductive technologies (ARTs), e.g. intracytoplasmic sperm injection (ICSI).
View Article and Find Full Text PDFDocumented Paternity Despite Azoospermia Post-vasectomy.
Cureus
October 2024
Obstetrics, Orlando Regional Medical Center, Orlando, USA.
Vasectomy is a permanent and safe method of male contraception. One commonly used definition of success is azoospermia in one or two semen analyses after 20 ejaculates after three months. Failure is higher if less than 1.
View Article and Find Full Text PDFTime will tell: time-lapse technology and artificial intelligence to set time cut-offs indicating embryo incompetence.
Hum Reprod
December 2024
IVIRMA Global Research Alliance, GENERA, Clinica Valle Giulia, Rome, Italy.
Study Question: Can more reliable time cut-offs of embryo developmental incompetence be generated by combining time-lapse technology (TLT), artificial intelligence, and preimplantation genetics screening for aneuploidy (PGT-A)?
Summary Answer: Embryo developmental incompetence can be better predicted by time cut-offs at multiple developmental stages and for different ranges of maternal age.
What Is Known Already: TLT is instrumental for the continual and undisturbed observation of embryo development. It has produced morphokinetic algorithms aimed at selecting embryos able to generate a viable pregnancy, however, such efforts have had limited success.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!