Aims And Objectives: The aims of this study were to translate the 20-item Questionnaire for the Assessment of Quality of Life in Asthma Patients (QLQ-Asthma) into Turkish and to assess the reliability and validity of the Turkish version of the Assessment of Quality of Life in Asthma Patients among Turkish adult asthmatic patients in Turkey.
Background: Asthma can adversely affect the physical, psychological and social domains of health-related quality of life. The Assessment of Quality of Life in Asthma Patients is a widely used instrument to measure quality of life in asthma patients. The Assessment of Quality of Life in Asthma Patients has not been validated in Turkey.
Design: Methodological research design.
Methods: This study describes the translation process of Assessment of Quality of Life in Asthma Patients into Turkish and tests its reliability and validity on quality of life in asthma patients. The study group was composed of 105 stable adult asthmatic patients. The questionnaire was translated using a back-translation technique. The statistical analysis was carried out using Cronbach's alpha to test the internal consistency of the Assessment of Quality of Life in Asthma Patients scale while exploratory factor analysis was carried out using principal component analysis with varimax rotation and Kaiser Normalisation to test its construct validity.
Results: The Cronbach's alpha coefficient reliability for the total scale was 0·84, and internal consistency reliability was in the acceptable range for this instrument. Results indicated that respondents did not have difficulty answering the questions in the Assessment of Quality of Life in Asthma Patients. Factor analysis resulted in five-factor structure: physical activities, role activities, emotions, social activities and health perceptions.
Conclusions: The Turkish version of the Assessment of Quality of Life in Asthma Patients is a reliable and valid supplementary measure of the quality of life in asthma patients, and it is a useful outcome measurement tool for clinical trials conducted in Turkey. RELEVANCE OF CLINICAL PRACTICE: The Assessment of Quality of Life in Asthma Patients scale is simple to administer, and Turkish researchers and health care providers can use the Assessment of Quality of Life in Asthma Patients to assess the asthma patients quality of life.
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http://dx.doi.org/10.1111/j.1365-2702.2010.03465.x | DOI Listing |
Nephrol Dial Transplant
November 2024
Department of Medicine and Nephrology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Background And Hypothesis: Daprodustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, is approved for treatment of anemia in dialysis patients with CKD in some parts of the world. This subgroup analysis examined the efficacy and safety of daprodustat versus darbepoetin alfa in patients with anemia of CKD undergoing peritoneal dialysis (PD).
Methods: ASCEND-D (NCT02879305) was an open-label, Phase 3 trial; patients with CKD were randomized to daprodustat daily and epoetin alfa (HD patients) or darbepoetin alfa (PD patients).
Curr Med Chem
January 2025
Shree S K Patel College of Pharmaceutical Education and Research, Ganpat University, Mahesana, Gujarat, 384012, India.
Therapeutic hurdles persist in the fight against lung cancer, although it is a leading cause of cancer-related deaths worldwide. Results are still not up to par, even with the best efforts of conventional medicine, thus new avenues of investigation are required. Examining how immunotherapy, precision medicine, and AI are being used to manage lung cancer, this review shows how these tools can change the game for patients and increase their chances of survival.
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January 2025
Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (S.G., Nimesh Patel, M.K., M.S.S.).
Int J Dermatol
January 2025
Division of Photobiology and Photomedicine, Department of Dermatology, Henry Ford Health, Detroit, MI, USA.
Few studies discuss the co-management of vitiligo and acquired hyperpigmentation disorders (AHD) such as melasma, erythema dyschromicum perstans, post-inflammatory hyperpigmentation, drug-induced hyperpigmentation, and lichen planus pigmentosus. This review discusses clinical studies examining co-management strategies and identifies current practice gaps. Dermatology Life Quality Index scores are higher in individuals with vitiligo or melasma.
View Article and Find Full Text PDFFront Child Adolesc Psychiatry
November 2022
School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
ADHD is associated with a number of developmental, emotional, social, academic, and cognitive health risks that can affect the adolescents' quality of life. There have been various guidelines published regarding the management of children with ADHD, however, it has been reported that physicians may not adequately screen for ADHD prior to surgery. To our knowledge, there are no such studies studying post-operative complications and outcome rates in adolescents with ADHD.
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