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Moebius syndrome and hypopituitarism: a case of multiple pituitary hormone deficiency and revision of the literature.
J Pediatr Endocrinol Metab
January 2025
Pediatrics, Fondazione IRCCS San Gerardo Dei Tintori, Monza, Italy.
Objectives: Moebius syndrome (MS) is a rare congenital non-progressive rhombencephalic disorder mostly characterised by abducens and facial nerve palsy, but with a multifaceted clinical presentation. Isolated or multiple pituitary hormone deficiencies in the setting of MS have been occasionally reported, but the simultaneous involvement of three or more hypothalamic-pituitary axes has never been described. We hereby report the case of a girl with MS that showed a co-occurrence of GH-, TSH- and ACTH-deficiency.
View Article and Find Full Text PDFB-cell infiltration distinguishes mucosal from skin patterns of rejection in facial vascularized composite allografts.
Am J Transplant
January 2025
Department of Surgery, Division of Plastic Surgery, Yale School of Medicine, New Haven, CT, USA. Electronic address:
Rejection monitoring in facial vascularized composite allotransplantation (fVCA) traditionally focuses on skin biopsies. However, mucosal rejection frequently presents with more pronounced signs of immune activity. To explore mechanistic differences between skin and mucosal rejection, rejection and non-rejection biopsies from allograft skin and oral mucosa of nine fVCA recipients were retrospectively analyzed using histology, multiplex immunostaining, and gene expression profiling, with peripheral blood mononuclear cells (PBMCs) quantified via mass cytometry (CyTOF).
View Article and Find Full Text PDFBrain connectivity for constructing new face representations in typical adults versus a prosopagnosic patient.
Neuroimage
January 2025
Department of Biological and Health Psychology, Faculty of Psychology, Universidad Autónoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain.
Will our brains get to know a new face better if we look at its external features first? Here we offer neurophysiological evidence of the relevance of external versus internal facial features for constructing new face representations, by contrasting successful face processing with a prototypical case of face agnosia. A woman with acquired prosopagnosia (E.C.
View Article and Find Full Text PDFDisseminated protothecosis in a dog coinfected with Hepatozoon canis and Ehrlichia canis.
Vet Res Commun
January 2025
Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina.
Protothecosis is a severe, emerging opportunistic infection caused by the saprophytic, achlorophyllous microalgae of the genus Prototheca. Though uncommon, human and animal cases are increasing worldwide, making awareness of this fungal-like pathogen important in both human and veterinary medicine. We report a fatal case of disseminated protothecosis caused by P.
View Article and Find Full Text PDFEfficacy of a topical live probiotic in improving skin health.
Int J Cosmet Sci
January 2025
Blis Technologies Limited, Dunedin, New Zealand.
Introduction: Micrococcus luteus is a commensal bacterial member of the human skin and is essential in keeping the balance among the various microbial flora of the skin. M. luteus strain Q24 or BLIS Q24™ was isolated from the skin of a healthy human adult and is known to produce a unique antimicrobial spectrum that is inhibitory towards pathogens associated with skin diseases.
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