Splenosis corresponds to an autotransplantation of splenic tissue, consecutive to a traumatic or surgical wound of the spleen. The peritoneal cavity is usually affected but intrathoracic nodules are also described, when simultaneous rupture of the spleen and diaphragmatic laceration exist. Diaphragmatic laceration may be subclinical. Lesions are generally asymptomatic and are a fortuitous finding in radiographs or by the surgeons in the majority of the cases. We report a case of pleural and pulmonary splenosis, mimicking pleural and pulmonary metastasis of a dorsal melanoma.
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http://dx.doi.org/10.1016/j.annpat.2010.07.002 | DOI Listing |
BMJ Case Rep
January 2025
Department of Radiology, Royal Perth Hospital, Perth, Western Australia, Australia.
Int J Surg
January 2025
Department of Thoracic Surgery, West China hospital, SiChuan University, Chengdu, China.
Background: While recent randomized controlled trials have demonstrated that sublobar resection is non-inferior to lobectomy, the comparative efficacy of these procedures remains uncertain for early-stage non-small cell lung cancer (NSCLC; ≤ 3 cm) exhibiting invasive features postoperatively, such as visceral pleural invasion (VPI) or spread through air spaces (STAS).
Materials And Methods: To identify eligible studies, a comprehensive search of PubMed, Embase, MEDLINE, the Cochrane Library, and Web of Science was conducted through 25 July 2024. Studies were screened according to predefined criteria in accordance with PRISMA guidelines.
Imaging-based spatial transcriptomics (ST) is evolving rapidly as a pivotal technology in studying the biology of tumors and their associated microenvironments. However, the strengths of the commercially available ST platforms in studying spatial biology have not been systematically evaluated using rigorously controlled experiments. In this study, we used serial 5-µm sections of formalin-fixed, paraffin-embedded surgically resected lung adenocarcinoma and pleural mesothelioma tumor samples in tissue microarrays to compare the performance of the single cell ST platforms CosMx, MERFISH, and Xenium (uni/multi-modal) platforms in reference to bulk RNA sequencing, multiplex immunofluorescence, GeoMx Digital Spatial Profiler, and hematoxylin and eosin staining data for the same samples.
View Article and Find Full Text PDFJ Comput Assist Tomogr
January 2025
Centre for Biomedical Engineering, Indian Institute of Technology Delhi.
Objective: Early diagnosis of primary and metastatic lung nodules is critical for effective therapeutic planning. Manual delineation of lung nodules is not time-efficient and is prone to human error as well as interobserver and intraobserver variability. This study aimed to address the unmet need for an open-source computer-aided detection (CAD) system for 3D segmentation of lung and metastatic lung nodules along with radiomic feature extraction.
View Article and Find Full Text PDFJ Comput Assist Tomogr
January 2025
Interventional Treatment, First Hospital of Qinhuangdao.
Objective: To confirm that saline sealing of the needle trace after computed tomography (CT)-guided lung biopsy reduces the incidence of pneumothorax and chest tube insertion, and to observe its effects on pulmonary hemorrhage and hemoptysis.
Materials And Methods: Patients who underwent CT-guided lung biopsy at our hospital between January 2018 and January 2024 were included in the study. Patients were divided into 2 groups according to whether the needle trace was sealed with saline after tissue sampling.
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