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Breastfeeding women in need of information about antiemetics for nausea and vomiting during pregnancy: a review of inquiries to a medicines information service.
Front Pharmacol
November 2023
Regional Medicines Information and Pharmacovigilance Centre (RELIS), Department of Clinical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway.
Article Synopsis
- The SafeMotherMedicine service frequently gets questions from breastfeeding women about using antiemetics for nausea and vomiting during pregnancy, but guidelines don’t address this specific situation.
- A review identified 97 inquiries about antiemetic medications, with most inquiries involving medications like meclizine and metoclopramide, primarily from women whose breastfed children were older than 6 months.
- There's a clear need for better information regarding the use of antiemetics during lactation to prevent unnecessary breastfeeding discontinuation among women experiencing nausea or vomiting during pregnancy.
Antihistamine use during breastfeeding with focus on breast milk transfer and safety in humans: A systematic literature review.
Basic Clin Pharmacol Toxicol
January 2022
PharmacoEpidemiology and Drug Safety, Department of Pharmacy, University of Oslo, Oslo, Norway.
Current data on use of antihistamines during breastfeeding and risks to the breastfed infant are insufficient. The aim of this systematic review was to provide an overview of studies measuring the levels of antihistamines in human breast milk, estimating the exposure for breastfed infants and/or reporting possible adverse effects on the breastfed infant. An additional aim was to review the antihistamine product labels available in the European Union (EU) and the United States.
View Article and Find Full Text PDFImpact of therapeutic rest in early labor on perinatal outcomes: a prospective study.
Am J Obstet Gynecol MFM
May 2021
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Women & Infants Hospital of Rhode Island, Warren Alpert Medical School of Brown University, Providence, RI (Dr Lewkowitz).
Background: Pain and exhaustion in early labor are important to address, yet treatment options are limited. Therapeutic rest has existed for decades, although medication regimens and management strategies vary. In addition, there are little prospective data on perinatal outcomes and patient satisfaction to support and guide its use as an outpatient pain control option.
View Article and Find Full Text PDFCurrent use of anticholinergic medications in a large naturalistic sample of psychiatric patients.
J Neural Transm (Vienna)
February 2021
Department of Psychiatry and Psychotherapy, Vitos Klinikum Hochtaunus, Friedrichsdorf, Germany.
Due to the high number of psychotropic drugs with anticholinergic potential, patients taking psychotropic drugs are at high risk for anticholinergic adverse drug reactions (ADRs). The aim of this study was to analyze the prevalence and type of pharmacodynamic anticholinergic drug-drug interactions in psychiatric patients. The retrospective longitudinal analysis used data from a large pharmacovigilance study conducted in ten German psychiatric hospitals.
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