Tourette syndrome (TS) bears a higher rate of inflammatory complications at the implanted hardware in deep brain stimulation (DBS).

Acta Neurochir (Wien)

Division of Functional Neurosurgery and Tourette Center, IRCCS Galeazzi Institute, via R. Galeazzi 4, 20161, Milan, Italy.

Published: March 2011

AI Article Synopsis

  • Deep brain stimulation (DBS) is widely used for movement disorders, but complications and side effects have been observed, particularly as its application expands to new conditions like Tourette syndrome (TS).
  • Research aims to evaluate hardware failures and infection rates in relation to DBS indications, highlighting potential risks associated with TS treatment.
  • Findings reveal a significant link between TS and increased risk of infective complications, suggesting that we must consider the unique characteristics of TS patients when recommending DBS.

Article Abstract

Background: Deep brain stimulation (DBS) is a commonly performed surgical technique for the treatment of movement disorders, and recent surgical trials concerning the treatment of a wider range of disorders have recently been published. Despite DBS being non-ablative and minimally invasive, numerous complications and side effects have been recorded. In particular, concerning the growing interest in novel indications for DBS, an enthusiastic approach has put neurosurgeons at risk of underestimating some of the complications that might be associated with specific characters of the treated disease.

Objective: Our objective was to evaluate hardware failures and rates of infective complications in correlation to the different indications to DBS, in order to ascertain whether DBS in Tourette syndrome (TS) is characterized by specific risks and pitfalls.

Methods: We retrospectively reviewed our experience of 531 procedures on 272 patients treated for various movement disorders, among which 39 patients were treated for conservative treatmentrefractory TS.

Results: A statistically significant association of infective complications was found with the TS subgroup.

Conclusions: It is our belief that specific behavioral characters of the TS patients may be put into association with this specific complication and need to be considered carefully when indicating DBS as treatment of choice for these patients.

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Source
http://dx.doi.org/10.1007/s00701-010-0851-yDOI Listing

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