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Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird.
Sci Rep
December 2024
Department of Biology, Queen's University, Kingston, ON, Canada.
Genetic diversity can influence fitness components such as survival and reproductive success. Yet the association between genetic diversity and fitness based on neutral loci is sometime very weak and inconsistent, with relationships varying among taxa due to confounding effects of population demography and life history. Fitness-diversity relationships are likely to be stronger and more consistent for genes known to influence phenotypic traits, such as immunity-related genes, and may also depend on the genetic differences between breeding partners.
View Article and Find Full Text PDFALLIN: A tool for annotation of a protein alignment combined with structural visualization.
J Gen Physiol
March 2025
Institute of Biophysics, National Research Council , Genova, Italy.
The physiological, functional, and structural properties of proteins and their pathogenic variants can be summarized using many tools. The information relating to a single protein is often spread among different sources requiring different programs for access. It is not always easy to select, simultaneously visualize, and compare specific properties of different proteins.
View Article and Find Full Text PDFNo Right Way: Removal of a Pencil Foreign Body From a Male Urethra.
Cureus
November 2024
Urology, Sunderland Royal Hospital, Sunderland, GBR.
Foreign body insertion into the urethra is uncommonly encountered in urology practice. Such insertion can result in a myriad of problems including bleeding, infectious sequelae, urinary retention, urethral injury or rupture, and resultant urethral stricture formation. This article describes a case in which an elderly male inserted a pencil into his urethra, which subsequently became lodged and required removal under regional anesthesia in the operating theater.
View Article and Find Full Text PDFSuccessful Endoscopic Removal of an Ingested Thumbtack Stuck in the Ileocecal Valve in a Patient With a Psychiatric Disorder.
Cureus
November 2024
Department of Emergency Medicine, Tokyo Women's Medical University, Tokyo, JPN.
Foreign body ingestion is sometimes missed during the initial evaluation of a patient with a psychiatric disorder in the emergency department. This is often due to a lack of awareness regarding the need for thorough physical and diagnostic imaging examinations. Additionally, the management of ingested foreign bodies is often controversial.
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