Dentinogenic ghost cell tumor (DGCT) is an uncommon locally invasive odontogenic tumor regarded by many as a variant of calcifying odontogenic cyst. The peripheral variant of this clinical rarity appears as a well-circumscribed mass mimicking a nonspecific gingival enlargement. Microscopic appearance of odontogenic epithelium admixed with focal areas of dentinoid formation and sheets of ghost cells giving the definitive diagnosis of dentinogenic ghost cell tumor imply that microscopic examination is compulsory for any gingival mass. Van Gieson histochemical stain further confirmed the nature of dentinoid-like material. A complete workup of a case of peripheral dentinogenic ghost cell tumor is presented in this paper and the current concept as well as the appraisal of literature is presented.
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http://dx.doi.org/10.1155/2010/519494 | DOI Listing |
Cureus
September 2024
Orthodontics and Dentofacial Orthopaedics, Army College of Dental Sciences, Secunderabad, IND.
A dentinogenic ghost cell tumor (DGCT) is a rare and locally aggressive benign mixed odontogenic tumor, histologically made up of ameloblast-like epithelial islands, ghost cells, and dentin-like material. This is a highly unusual example of DGCT combined with an odontoma in a 13-year-old female patient affecting the right maxilla. On radiographic examination, ill-defined radiolucency with right maxillary sinus obliteration and involvement of permanent maxillary right first and second molars were noted.
View Article and Find Full Text PDFHead Neck Pathol
October 2024
Surgical Pathology Laboratory, Oral Pathology Department, Facultad de Odontología, Universidad de Buenos Aires, M.T. Alvear 2142. (C1122AAH), Ciudad Autónoma de Buenos Aires, Argentina.
Autops Case Rep
August 2024
Department of Oral Medicine and Radiology, Post Graduate Institute of Dental Sciences, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, Haryana, India.
Dentinogenic ghost cell tumor (DGCT) is a rare benign neoplasm form of calcifying odontogenic cyst (COC) characterized by ghost cells. Although benign, it presents an aggressive behavior. DGCT accounts for 2% to 14% of all COCs and less than 0.
View Article and Find Full Text PDFOral Radiol
October 2024
Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.
A dentinogenic ghost cell tumor (DGCT) is a rare benign odontogenic tumor that commonly shows characteristics of solid proliferation and has a relatively high risk of recurrence after surgical treatment. We herein report a case of a central DGCT that occurred in the maxilla and resulted in bone expansion. This study highlights new imaging findings (particularly magnetic resonance imaging) along with histopathological observations.
View Article and Find Full Text PDFHistopathology
December 2024
Faculty of Dentistry, Oral and Craniofacial Science, King's College London, London, UK.
Adenoid ameloblastoma (AA) was recently recognised as a separate tumour type in the most recent World Health Organisation (WHO) classification of head and neck tumours. This decision has been considered controversial by several groups, who have described AA as a subtype of ameloblastoma, a hybrid odontogenic tumour or to fall within the spectrum of other recognised odontogenic tumours, including dentinogenic ghost cell tumour and adenomatoid odontogenic tumour. Here we review the reasons for the WHO decision to classify AA as a separate tumour type.
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