AI Article Synopsis
- A study analyzed 110 Streptococcus dysgalactiae subsp. equisimilis isolates using PCR to detect the presence of the SICG gene, finding it in 19 strains (17%).
- Of these 19 strains, 11 (55%) were linked to invasive diseases, with all strains displaying group G carbohydrate and most having specific emm types (stG643 and stG2078).
- While no direct link was found between the presence of the SICG gene and the severity of infection, further research could clarify its role in the virulence of S. dysgalactiae infections.
Article Abstract
Streptococcus dysgalactiae subsp. equisimilis isolates (n = 110) were analyzed by PCR to determine whether the gene encoding SICG, a homolog of Streptococcus pyogenes SIC, was present. Nineteen strains (17%) had this gene of which 11 (55%) were isolated from patients with invasive disease. All 19 strains possessed group G carbohydrate. Molecular characterization of emm type revealed that the majority of emm sequences were stG643 and stG2078. Only the N-terminal sequence of SICG was similar to that of SIC in S. pyogenes. Although we found no significant relationship between pathogenic severity and sicG possession, further investigation into the mechanism of SICG may elucidate the virulence in S. dysgalactiae subsp. equisimilis infection.
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| http://dx.doi.org/10.1007/s00284-010-9798-8 | DOI Listing |
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