We report on a patient with breast cancer in whom there were areas of the tumor that were 3+ positive and negative for HER2 neu by immunohistochemistry, adjacent to each other. Depending on the area tested the results were completely different. The clinical implications are important. We recommend retesting a large portion of the tumor in all cases of initially negative test results.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968767 | PMC |
| http://dx.doi.org/10.1159/000319020 | DOI Listing |
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