Objectives: Sexuality on the whole and erectile response particularly are not alien to psychosocial and couple features. We review al psychological and couple features that interfere on erection and also point out the interventional directions of couple therapy that give the best results in the treatment of erectile dysfunction.
Methods: We performed a bibliographic review about the psychological and social features under the current way of life in relation to erectile response physiology, in addition to review different models of couple therapy.
Results/conclusions: The separation of the couple reproduction-pleasure achieved in the 50's enabled a progressive claim from women of their need to be satisfied, representing one of the reasons that led to the phenomenon of "performance anxiety" that, altogether with some toxic habits (Tobacco consumption, alcohol, drugs, sedentary life, etc) help the appearance of erectile dysfunction. When psychological factors are an important part of the problem, couple sexual therapy in combination with phosphodiesterase 5 inhibitors is the therapy of choice.
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Medicine (Baltimore)
November 2024
College of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Utilizing network pharmacology and molecular docking, we evaluated the possible pharmacological mechanism of Danggui Sini Decoction (DGSND) for treating erectile dysfunction (ED). DGSND's chemical components and targets were found utilizing the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP). Disease-related genes associated with ED were identified through GeneCards, OMIM, TTD, DrugBank, and DisGeNET databases.
View Article and Find Full Text PDF3D Print Med
January 2025
Department of Surgical & Interventional Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Background: Penile implant surgery is the standard surgical treatment for end-stage erectile dysfunction. However, the growing complexity of modern high-tech penile prostheses has increased the demand for more practical training opportunities. The most advanced contemporary training methods involve simulation training using cadavers, with costs exceeding $5,000 per cadaver, inclusive of biohazard fees.
View Article and Find Full Text PDFSex Med
December 2024
Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, FL 32306, United States.
Background: Erectile dysfunction is a condition with a rapidly increasing prevalence globally with a strong correlation to the increase in obesity and cardiovascular disease rates.
Aim: The aim of the current study is to investigate the potential role of tubacin, a histone deacetylase 6 (HDAC6) inhibitor, in restoring erectile function in a hypercholesterolemia-induced endothelial dysfunction model.
Methods: Thirty-nine male C57Bl/6 J mice were divided into 3 groups.
Andrology
January 2025
Department of Pharmacology, Faculty of Pharmacy, Ankara University, Ankara, Turkey.
Background: Androgen deprivation is associated with erectile dysfunction (ED). In different animal models, sulfur dioxide (SO) donors NaSO and NaHSO reduced oxidative stress, fibrosis, and inflammation which contribute to the pathogenesis of androgen deprivation-induced ED, however the effect of SO donors on ED in castrated rats were not known.
Objective: To investigate the therapeutic effect of SO donors, NaSO/NaHSO, on ED in castrated rat model.
J Sex Med
January 2025
Department of Urology, University Vita-Salute San Raffaele, 20132 Milan, Italy.
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