Enamel of human and bovine teeth was found to show sorption of free calcium ions after damage caused by short-term exposure to diluted hydrochloric acid or mechanical damage. The experiment was carried out using radioisotopes 32P and 45Ca and it was shown that majority of incorporated ions remained in the enamel after prolonged washing out with water as well as after brushing with toothpaste. A considerable stability of binding of the incorporated phosphate ions was noted in the damaged enamel after exposure to calcium salt solution, and marked stability of binding of the incorporated calcium ions after exposure to phosphate solution.
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J Biochem Mol Toxicol
February 2025
Calcium Signaling Laboratory, Veterans Affairs Medical Center, Research Service, Washington, District of Columbia, USA.
Crystalline nephropathy (CN) is characterized by deposition of microcrystals within the kidney tubular microstructure, specifically in the renal tubular cells. Nephropathic conditions have been observed in kidney stone patients as nephrocalcinosis, resulting from the deposition of calcium phosphate (CaP) microcrystals mainly within the renal tubule. CaP microcrystals trigger nephrotoxicity and cell death leading to acute and chronic kidney disease and in some cases end stage renal disease.
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January 2025
Department of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, P. R. China.
Mesenchymal stem cells (MSCs) transplantation is a promising therapeutic strategy for ischemic stroke. However, the survival of transplanted MSCs is often compromised by the excessive levels of reactive oxygen species (ROS) and calcium ions (Ca) in the ischemic microenvironment following blood flow occlusion. In this study, a protective strategy is developed using functional nanomaterials to escort and shield MSCs.
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January 2025
College of Civil Engineering and Mechanics of Lanzhou University, Lanzhou 730000, China.
The controllable regulation of immune and osteogenic processes plays a critical role in the modification of biocompatible materials for tissue regeneration. In this study, titanium dioxide-europium coatings (MAO/Eu) were prepared on the surface of a titanium alloy (Ti-6Al-4V) a one-step process combining microarc oxidation (MAO) and doping. The incorporation of Eu significantly improved the hydrophilic and mechanical properties of the TiO coatings without altering their morphology.
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State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address:
Probiotics have brought many health benefits to the human body. However, their viability during gastrointestinal transit is a concern. Therefore, this study selected Mesona chinensis polysaccharide (MCP), an edible natural polysaccharide, and constructed a new type of microcapsules using MCP as raw material to prepare cross-linked calcium ions through a microfluidic system as an ideal intestinal targeting carrier to achieve precise delivery of bioactive substances.
View Article and Find Full Text PDFInsect Biochem Mol Biol
January 2025
Division of Parasitic Diseases and Malaria, Entomology Branch, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, NE, Atlanta, GA 30329, USA.
With the increasing concern of potential loss of transgenic mosquitoes which are candidates as new tools for mosquito-borne disease control, methods for cryopreservation are actively under investigation. Methods to cryopreserve Anopheles gambiae sperm have recently been developed, but there are no artificial insemination or in vitro fertilization tools available. As a step to achieve this, we sought to identify a suitable medium for in vitro incubation of An.
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