Objective: To survey patient attitudes toward fertility preservation techniques in the case of infertility from cancer treatment.
Study Design: A cross-sectional survey on adolescent cancer patients (ACPs) aged 15-21 years and their parents, as well as on breast cancer patients (BCPs).
Results: A total of 69% of ACPs were aware of the problem of infertility. However, only 31% recalled being spoken to about treatment effects on fertility. Parents were significantly more likely to have been spoken to (58% vs. 31%, p < 0.022) and tended to be more interested in fertility preservation. The groups were in agreement that cancer therapy should not be delayed. Of the BCPs, 67% expressed substantial concern regarding infertility. They were more likely to have been spoken to and tended to be younger and nulliparous, although statistical significance was not reached. Again, most were unwilling to delay therapy.
Conclusion: There is an interest infertility preservation amongst our patients, but the medical information received may influence, to a certain extent, the attitudes of the patients. Greater emphasis should therefore be placed on counseling the patient during the treatment planning process.
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J Assist Reprod Genet
January 2025
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Northwestern University, Chicago, IL, USA.
Purpose: To develop a predictive model for estimating the total dose of gonadotropins and the number mature oocytes in planned oocyte cryopreservation cycles.
Methods: In this retrospective study, oocyte cryopreservation cycles recorded in the Society for Assisted Reproductive Technology Clinic Outcome Reporting System Database from 2013 to 2018 were analyzed. Bivariate copula additive models for location, scale, and shape were performed to create a predictive model for estimating total dose of gonadotropins and number of mature oocytes.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
December 2024
Department of Obstetrics and Gynecology, Women and Children's Hospital of Ningbo University,Ningbo,Zhejiang 315000,China.
Objective To compare the safety and efficacy of fertility-sparing surgery in patients with ovarian borderline tumors (BOT). Methods A total of 121 BOT patients undergoing fertility-sparing surgery between January 2010 and October 2022 were retrospectively analyzed.The univariate analysis,multivariate analysis,and survival curves were employed to evaluate the clinicopathological and surgical variables and fertility.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
The Key Laboratory of Fertility Preservation and Maintenance of the Ministry of Education, Ningxia Medical University, Yinchuan 750004, China.
The male reproductive impairment caused by environmental estrogens (EEs) stands as a pivotal research area in environmental toxicology. Alpha2-macroglobulin (A2M) emerges as a promising molecule capable of counteracting oxidative stress induced by EEs. This study conducted exposure experiments spanning PND1 to PND56 employing ICR mice, aiming to delve into the expression patterns of A2M and its modulated IL-6 in the testicular tissue of mice subsequent to diethylstilbestrol (DES) and benzophenone (BP) exposure, while elucidating the pivotal role of ERs in this intricate process.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Obstetrics and Gynecology, District Hospital of Schaffhausen, 8208 Schaffhausen, Switzerland.
Ethanol sclerotherapy (EST) has gained attention as a minimally invasive treatment option for ovarian endometriomas, particularly in infertile women with endometrioma undergoing in vitro fertilization (IVF). Endometriomas are associated with decreased ovarian reserve and impaired fertility outcomes, and traditional surgical approaches, such as cystectomy, often lead to further reductions in ovarian reserve. Ethanol sclerotherapy offers a potential alternative that preserves ovarian function while effectively managing endometriomas.
View Article and Find Full Text PDFBiomedicines
December 2024
Third Department of Obstetrics and Gynecology, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, 1 Rimini, 124 62 Athens, Greece.
: Endometriosis is characterized by the presence of endometrial tissue outside the uterus. Beyond medical treatment, surgical intervention is also a viable consideration. However, current guidelines do not clearly indicate whether laparoscopic cystectomy, ablative methods (CO laser vaporization, plasma energy), or sclerotherapy is the preferred option.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!