The Knoevenagel-Doebner reaction on 1,2-O-(2,2,2-trichloroethylidene) derivatives of D-gluco- and D-manno-furanose.

The synthesis of new α,β-unsaturated furanuronic acid derivatives of α-gluco-, β-gluco- and β-manno-chloraloses via a convenient one pot procedure using the Knoevenagel-Doebner reaction approach are described. The dialdofuranose derivatives were reacted with malonic acid under Knoevenagel-Doebner reaction conditions and (E)-α,β-unsaturated furanuronic acid derivatives were obtained.