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High Revision Rate After Transphyseal ACL Reconstruction in Skeletally Immature Patients.
J Pers Med
November 2024
Center for Diagnostic and Interventional Radiology and Nuclear Medicine, Charité-University Medicine Berlin, 10117 Berlin, Germany.
There remains considerable debate regarding the optimal management of anterior cruciate ligament (ACL) injuries in skeletally immature patients. This study aims to evaluate the clinical outcomes of transphyseal ACL reconstruction in patients with open growth plates. This retrospective study included skeletally immature patients with full-thickness ACL tears and confirmed open physis.
View Article and Find Full Text PDFThe Nematocidal Effect of Leiurus quinquestratus Scorpion Venom on Toxocara canis in Mice Model.
J Exp Zool A Ecol Integr Physiol
December 2024
Zoology Department, Faculty of Science, Tanta University, Tanta, Egypt.
One neglected zoonotic illness is toxocariasis. There are not enough anthelmintic drugs in the market to treat low-effectiveness toxocariasis against migrating larvae. Therefore, it is critical to find new, safe alternatives to toxocariasis treatment today.
View Article and Find Full Text PDFIntra-articular injection of vancomycin after arthrotomy closure following gentamicin-impregnated bone cementation in primary total knee arthroplasty provides a high intra-articular concentration while avoiding systemic toxicity: a prospective study.
J Orthop Surg Res
December 2024
Department of Joint Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266000, China.
Background: This study aimed to elucidate the safety and intra-articular elution profiles of vancomycin and gentamicin bone cement in patients undergoing primary total knee arthroplasty (TKA), with a focus on serum safety thresholds and therapeutic efficacy.
Methods: Consecutive patients who underwent unilateral primary TKA were prospectively enrolled. The implants were fixed using gentamicin-impregnated bone cement, and after arthrotomy closure, 1000 mg of vancomycin suspended in 25 mL of normal saline was directly injected into the joint.
Intracranial complications in adult patients with severe pneumococcal meningitis: a retrospective multicenter cohort study.
Ann Intensive Care
December 2024
Université Paris Cité, INSERM U1137, Paris, F-75018, France.
Background: We aimed to investigate the association of intracranial complications diagnosed on neuroimaging with neurological outcomes of adults with severe pneumococcal meningitis.
Methods: We performed a retrospective multicenter study on consecutive adults diagnosed with pneumococcal meningitis requiring at least 48 h of stay in the intensive care unit (ICU) and undergoing neuroimaging, between 2005 and 2021. All neuroimaging were reanalyzed to look for intracranial complications which were categorized as (1) ischemic lesion, (2) intracranial hemorrhage (3) abscess/empyema, (4) ventriculitis, (5) cerebral venous thrombosis, (6) hydrocephalus, (7) diffuse cerebral oedema.
Competing risks multi-state model for time-to-event data analysis of HIV/AIDS: a retrospective cohort national datasets, Ethiopia.
BMC Infect Dis
December 2024
Department of Epidemiology and Biostatistics, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.
Introduction: Tuberculosis (TB) remains the most common opportunistic infection and leading cause of death among individuals living with HIV/AIDS in Ethiopia. Its significant impact on morbidity and mortality underscores the crucial link between these two diseases. While the advent of antiretroviral therapy (ART) has led to a dramatic decline in mortality rates among HIV/AIDS patients, TB continues to pose a substantial threat.
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