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Bifidobacterium adolescentis is resistant to pyrazinamide, isoniazid, and streptomycin.
Sci Rep
November 2024
Department of Biochemistry, CSIR- Central Food Technological Research Institute (CFTRI), Mysuru, Karnataka, 570020, India.
Article Synopsis
- The study investigates how Bifidobacterium adolescentis resists first-line anti-tubercular drugs like isoniazid, pyrazinamide, and streptomycin, finding that even at high drug concentrations, the bacteria continue to grow unaffected.
- Some bacteria exhibited strong aggregation, which may help protect them from drug toxicity, and further microscopic analysis revealed that certain bacteria became elongated and protruded.
- Whole genome sequencing showed few antibiotic resistance genes or bacteriocins present, but some hypothetical proteins were observed, with 3D structure analyses suggesting possible interactions with specific ligands.
Protective Role of Vitamin B6 Against Teratogenic Effects Induced by Lead in Chick Embryo.
Birth Defects Res
December 2024
Department of Zoology, University of Sargodha, Sargodha, Punjab, Pakistan.
Article Synopsis
- Lead exposure has increased since the industrial revolution, posing serious health risks as it serves no purpose in the human body and is still used in various industries, like battery manufacturing.* -
- This study examined the harmful effects of lead on chick embryos, noting significant growth reductions and deformities, while also assessing the potential of vitamin B6 to counteract these effects.* -
- Results showed that vitamin B6 improved embryo weight and reduced lead's negative impacts, indicating it may help protect against lead toxicity during development.*
Characterization of cross-reactive, non-neutralizing monoclonal antibodies against a pandemic GII.4 norovirus variant.
Microbiol Spectr
October 2024
Division of Viral Products, CBER, FDA, Silver Spring, Maryland, USA.
Unlabelled: Antibodies are thought to play a major role in protection against human norovirus infection. Mouse humoral responses closely mimic those of humans; thus, mouse models are used to characterize norovirus epitopes on the major viral capsid protein, VP1. We have developed a panel of mouse monoclonal antibodies (mAbs) produced against the last pandemic variant to emerge, Sydney 2012.
View Article and Find Full Text PDFMolecular and Morphological Characteristics of a Novel Cyst Nematode in the Rhizosphere of DC. in Gansu Province, Northwest China.
Pathogens
October 2024
Biocontrol Engineering Laboratory of Crop Disease and Pests of Gansu Province, College of Plant Protection, Gansu Agricultural University, Lanzhou 730070, China.
Cyst nematodes are obligate parasitic nematodes found in the fields of many cultivated crops. These nematodes, which have great economic importance, pose a threat to food security, though they are frequently ignored or misdiagnosed as pests because of covert parasitism. A cyst nematode population parasitizing on DC.
View Article and Find Full Text PDFPentalogy of Cantrell Marked With Ectopia Cordis, Gastroschisis, and Cystic Hygroma in the First Trimester: A Rare Case.
Cureus
September 2024
Department of Obstetrics and Gynecology, South Central Regional Medical Center, Laurel, USA.
Pentalogy of Cantrell is a rare congenital syndrome characterized by defects in the abdominal wall, sternum, diaphragm, and heart. A severe manifestation of this syndrome is ectopia cordis, where the heart is located partially or entirely outside the chest cavity. Gastroschisis involves a defect in the abdominal wall, where the intestines protrude outside the abdomen without a protective membrane.
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