[Serum levels of lipids, lipoproteins and apoproteins (A, A-1, and B) in diabetes mellitus type I. Their relationship with the degree of metabolic control].

We studied the role played by an adequate metabolic control on lipids, lipoproteins, apolipoprotein A (apo A), apolipoprotein A-I (apo A-I) and apolipoprotein B (apo B), in 30 type I diabetic patients at different states of the diseases. We did not observe significant differences, comparing the mean values of lipids and lipoproteins, in the group of patients with good metabolic control. Patients, without appropriate diabetic control, showed values significantly higher in triglycerides and VLDL-C and significantly lower in HDL-C compared to the values of the control group. In respect of the apoprotein pattern, we did not observe significant differences between controlled diabetic patients; while non-controlled diabetic patients showed mean values higher of apo B, but no differences between apo A and apo A-I. Our results support the previous evidence published by other authors, confirming the relationship between an adequate diabetic control and the onset of lipoprotein changes, that can play a causal role in arteriosclerosis.