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The Efficacy of Cryoneurolysis on Chronic Pain in Patients with Knee Osteoarthritis; A Double-blinded Randomized Controlled Sham Trial.
Anesthesiology
January 2025
Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.
Background: The objective was to investigate if cryoneurolysis were superior to sham in reducing pain intensity in patients with chronic knee osteoarthritis. We hypothesized that cryoneurolysis was an effective and safe therapy to reduce chronic pain in patients with knee osteoarthritis.
Methods: The study was a randomized, double-blind, sham-controlled.
Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations: A Case Report.
Cureus
December 2024
Internal Medicine, Unidade Local De Saúde De São João, Porto, PRT.
Hypereosinophilic syndrome (HES) is marked by eosinophilic infiltration and the release of inflammatory mediators that cause damage to multiple organs. Despite careful evaluation of hypereosinophilia, the etiology of most cases remains undefined. Eosinophils may cause damage in almost all organs, and most patients present with dermatological manifestations.
View Article and Find Full Text PDFPrimary Cutaneous Marginal Zone Lymphoma and : Still an Open Book.
J Cutan Med Surg
January 2025
Division of Dermatology, Jewish General Hospital/Lady Davis Institute for Medical Research, McGill University, Montreal, QC, Canada.
Bloodstream infection in a neonatal intensive care unit: Epidemiology, Antifungal susceptibility and new drug delivered strategies.
J Mycol Med
January 2025
Mycology Laboratory, School of Pharmacy, Midwestern Paraná State University, UNICENTRO, PR, Brazil. Electronic address:
Bloodstream infection in neonates is a complicated disease and presents a major challenge both in diagnosis and in therapeutic intervention. The focus of the present study was to investigate the incidence, the species distribution and the risk factors associated with mortality of bloodstream infections in a neonatal intensive care unit (NICU) and evaluating the antifungal susceptibility of traditional antifungal drugs and three nanoparticle-based drug delivery systems based on nanoparticles. A total of 458 patients were evaluated, and 9.
View Article and Find Full Text PDFA Rare Head and Neck Tumor: Making Simple Things Complicated.
Cureus
December 2024
Pathology, Sir Ganga Ram Hospital, New Delhi, IND.
Primary cutaneous anaplastic large cell lymphoma (ALCL) is a very uncommon type of CD30-positive T-cell lymphoma, and it very rarely affects the forehead. We report the case of a 68-year-old male presenting with an ulcerative lesion on the right forehead, initially suspected as a benign condition. Fine needle aspiration suggested a lymphoproliferative disorder, with biopsy and immunohistochemistry confirming primary cutaneous ALCL (CD30-positive, anaplastic lymphoma kinase [ALK]-negative).
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