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Emergence and clinical challenges of ST11-K64 carbapenem-resistant Klebsiella pneumoniae: molecular insights and implications for antimicrobial resistance and virulence in Southwest China.
BMC Infect Dis
January 2025
Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Background: In clinical practice, the emergence of ST11-K64 carbapenem-resistant Klebsiella pneumoniae (ST11-K64 CRKP) has become increasingly alarming. Despite this trend, limited research has been conducted to elucidate the clinical and molecular characteristics of these strains.
Objectives: This study aimed to comprehensively investigate the clinical characteristics, antimicrobial resistance patterns, resistance and virulence-associated genes, and molecular epidemiology of ST11-K64 CRKP in Southwest China.
Machine Learning Model for Risk Prediction of Prolonged Intensive Care Unit in Patients Receiving Intra-aortic Balloon Pump Therapy during Coronary Artery Bypass Graft Surgery.
J Cardiovasc Transl Res
December 2024
Department of Cardiovascular Surgery, The Yancheng School of Clinical Medicine of Nanjing Medical University, 02 Xinduxi Road, Yancheng, 224000, China.
This study aimed to construct machine learning models and predict prolonged intensive care units (ICU) stay in patients receiving perioperative intra-aortic balloon pump (IABP) therapy during cardiac surgery. 236 patients were divided into the normal (≤ 14 days) and prolonged (> 14 days) ICU groups based on the 75th percentile of ICU duration across the entire cohort. Seven machine learning models were trained and validated.
View Article and Find Full Text PDFCervical spinal cord injury following osteophyte excision for respiratory distress caused by diffuse idiopathic skeletal hyperostosis associated with ossification of posterior longitudinal ligament: a case report and literature review.
BMC Musculoskelet Disord
December 2024
Department of Orthopedic Surgery, Nara Medical University, 840 Shijo-cho Kashihara City, Nara, 6348522, Japan.
Background: Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic non-inflammatory disorder characterized by enthesopathy and osteophyte formation. DISH can also cause several other symptoms. Limited range of motion (ROM) is the most common symptom; however, dysphagia and respiratory distress are clinically important symptoms.
View Article and Find Full Text PDFSubmucosal Thyroarytenoid Myectomy with Arytenoidectomy in Treating Bilateral Vocal Fold Immobility.
Laryngoscope
November 2024
Division of Otolaryngology, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Article Synopsis
- Surgery for bilateral vocal fold immobility (BVFI) seeks to improve airway function while maintaining voice and swallowing capabilities, and current methods often result in challenging healing outcomes and granulation tissue issues.
- A case-series analysis of eight BVFI patients who underwent a new surgical technique showed successful decannulation rates and improved respiratory symptoms without negatively impacting long-term voice or swallowing functions.
- The proposed method, submucosal thyroarytenoid myomectomy with arytenoidectomy, effectively utilizes body’s natural healing processes while preserving important laryngeal structures, enhancing overall treatment effectiveness for BVFI.
Epidemiology, presentation, management and outcomes of patients with acute epiglottitis - A 10-year retrospective study based on a tertiary hospital in northern China.
Eur Arch Otorhinolaryngol
January 2025
Department of Otolaryngology, Hebei Eye Hospital, No.399, East Quanbei Street, Xingtai, 054001, Hebei Province, China.
Article Synopsis
- * Common symptoms included sore throat (93.17%) and dysphagia (48.09%), with a notable increase in AE cases observed annually.
- * Despite a low incidence of required airway interventions, the study underscores the importance of early identification of risk factors and the need for effective management strategies to prevent severe complications.
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