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Survival, Tumor Control, and Safety Outcomes of Proton Therapy in Sinonasal Cancer Population: A Systematic Review and Meta-Analysis.
Head Neck
January 2025
Department of Otolaryngology- Head and Neck Surgery, Mayo Clinic Florida, Jacksonville, Florida, USA.
Background: In sinonasal cancer (SNC), treatment with proton therapy (PT) provides excellent local control, especially after gross total resection. Because of the heterogeneity and rarity of this disease site, a comprehensive assessment of toxicity, survival, and control rates is lacking. Our primary objective was to assess the toxicity outcomes of PT in SNC patients, with a secondary aim of assessing survival and tumor control after PT.
View Article and Find Full Text PDFExploring timely and safe discharge from ICU: a comparative study of machine learning predictions and clinical practices.
Intensive Care Med Exp
January 2025
Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Background: The discharge practices from the intensive care unit exhibit heterogeneity and the recognition of eligible patients for discharge is often delayed. Recognizing the importance of safe discharge, which aims to minimize readmission and mortality, we developed a dynamic machine-learning model. The model aims to accurately identify patients ready for discharge, offering a comparison of its effectiveness with physician decisions in terms of safety and discrepancies in discharge readiness assessment.
View Article and Find Full Text PDFEnhancing Research Education Through PhD and DNP Collaboration: Scoping Review and Case Study.
Nurs Educ Perspect
January 2025
About the Authors Rachel McMahan Thomas, PhD, MSN, FNP-BC, is assistant professor, School of Nursing, Brooks College of Health, University of North Florida, Jacksonville, Florida. Sandra D. Shapiro, DNP, MSN-CNL, FNP-BC, is assistant professor, School of Nursing, Brooks College of Health, University of North Florida. For more information, contact Dr. Thomas at
Aim: This article presents details about the literature on challenges and strategies for DNP-PhD nurse collaborations. A secondary aim is to present a case study about a BSN research course co-created by the authors, who are PhD and DNP nurses.
Background: Compared to the well-established role of the PhD-prepared nurse, the role of the doctor of nursing practice (DNP) is in its infancy.
A case report of long-latency evoked diaphragm potentials after exposure to acute intermittent hypoxia in post-West Nile virus meningoencephalitis.
J Neurophysiol
February 2025
Breathing Research and Therapeutics Center, Department of Physical Therapy, University of Florida, Gainesville, Florida, United States.
We present a case report of a 42-year-old female with post-West Nile virus meningoencephalitis who exhibited unique, long-latency diaphragm potentials evoked by transcranial and cervical magnetic stimulation after exposure to acute intermittent hypoxia (AIH). The subject was recruited for a study investigating AIH effects on respiratory motor function in healthy individuals. She had contracted West Nile virus infection 5 years before assessment that resulted in hospitalization and persistent allodynia but was not reported to the research team.
View Article and Find Full Text PDFInvestigating Metabolic Phenotypes for Sarcoidosis Diagnosis and Exploring Immunometabolic Profiles to Unravel Disease Mechanisms.
Metabolites
December 2024
Division of Pulmonary, Critical Care, and Sleep, College of Medicine-Jacksonville, University of Florida, Jacksonville, FL 32209, USA.
Sarcoidosis is a granulomatous disease affecting multiple organ systems and poses a diagnostic challenge due to its diverse clinical manifestations and absence of specific diagnostic tests. Currently, blood biomarkers such as ACE, sIL-2R, CD163, CCL18, serum amyloid A, and CRP are employed to aid in the diagnosis and monitoring of sarcoidosis. Metabolomics holds promise for identifying highly sensitive and specific biomarkers.
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